2,3,5,6-Tetrafluoro-4-hydrazinylpyridine CAS 1735-44-0
| CAS No. | 1735-44-0 |
| Molecular Formula | C5H3F4N3 |
| Molecular Weight | 181.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,3,5,6-Tetrafluoro-4-hydrazinylpyridine (CAS 1735-44-0) is a high-purity analytical reference standard with the molecular formula C5H3F4N3 and a molecular weight of 181.09 g/mol.
2,3,5,6-Tetrafluoro-4-hydrazinylpyridine (C5H3F4N3) contains a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H3F4N3 |
| Molecular Weight | 181.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Tetrafluoro Standards
- 2,3,5,6-Tetrafluoro-4-methoxypyridine (CAS 2375-90-8)
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- 2,3,5,6-Tetrafluoro-N-methylaniline (CAS 4920-56-3)
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Recommended Standards
- 3-Fluoro-4-(trifluoromethoxy)pyridine (CAS 1361880-79-6)
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- 2-(Difluoromethyl)-4,5-difluoropyridin-3-ol (CAS 1804453-95-9)
- 4-(4-(Tert-butyl)phenyl)-4-oxo-2-((5-(trifluoromethyl)pyridin-2-yl)thio)butanoic acid (CAS 279691-64-4)
- 2-((3,5-Difluorophenoxy)methyl)benzaldehyde (CAS 1443348-44-4)
- tert-Butyl 2-(2-(cyclohexylamino)pyridin-3-yl)pyrrolidine-1-carboxylate (CAS 1352482-45-1)
- 3-((4-Nitro-1h-pyrazol-1-yl)methoxy)benzaldehyde (CAS 1006436-08-3)
- Tetrahydro-2H-thiopyran-2-carboxamide (CAS 18729-18-5)
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