N-(2,2-Difluoro-6-nitro-benzo[1,3]dioxol-5-yl)acetamide CAS 1736-66-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1736-66-9
Molecular FormulaC9H6F2N2O5
Molecular Weight260.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(2,2-Difluoro-6-nitro-benzo[1,3]dioxol-5-yl)acetamide CAS 1736-66-9 chemical structure

Description

The occurrence of N-(2,2-Difluoro-6-nitro-benzo[1,3]dioxol-5-yl)acetamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

N-(2,2-Difluoro-6-nitro-benzo[1,3]dioxol-5-yl)acetamide (CAS 1736-66-9), molecular formula C9H6F2N2O5 and molecular weight 260.15 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C9H6F2N2O5, N-(2,2-Difluoro-6-nitro-benzo[1,3]dioxol-5-yl)acetamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 260.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(2,2-Difluoro-6-nitro-benzo[1,3]dioxol-5-yl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H6F2N2O5
Molecular Weight260.15 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF-containing
Nitrogen Atoms2

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