rel-(1R,2S)-1-Amino-2-phenylcyclobutane-1-carboxylic acid hydrochloride CAS 17382-16-0
| CAS No. | 17382-16-0 |
| Molecular Formula | C11H13NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 227.69 g/mol gives rel-(1R,2S)-1-Amino-2-phenylcyclobutane-1-carboxylic acid hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies rel-(1R,2S)-1-Amino-2-phenylcyclobutane-1-carboxylic acid hydrochloride (CAS 17382-16-0), a certified reference material (molecular formula C11H13NO2HCl, MW 227.69 g/mol) for analytical method development and quality control.
The molecular framework of rel-(1R,2S)-1-Amino-2-phenylcyclobutane-1-carboxylic acid hydrochloride (C11H13NO2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures rel-(1R,2S)-1-Amino-2-phenylcyclobutane-1-carboxylic acid hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H13NO2 HCl |
| Molecular Weight | 227.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
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- tert-Butyl 7-fluoroindoline-1-carboxylate (CAS 1823295-30-2)
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- Ethyl 1-(4-fluorophenyl)-1H-1,2,4-triazole-3-carboxylate (CAS 1613022-95-9)
- Ticagrelor impurity 161 (CAS 1157692-93-7)
- Polyphemusin II-Derived Peptide (CAS 229030-20-0)
Why CATO?
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