Amylmetacresol EP Impurity E CAS 173851-66-6
| CAS No. | 173851-66-6 |
| Molecular Formula | C12H16O2 |
| Molecular Weight | 192.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Amylmetacresol EP Impurity E (CAS 173851-66-6), a pharmacopoeial impurity reference standard (molecular formula C12H16O2, MW 192.25 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Amylmetacresol EP Impurity E (C12H16O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Amylmetacresol EP Impurity E meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16O2 |
| Molecular Weight | 192.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2006 |
Related Amylmetacresol Standards
- Amylmetacresol EP Impurity E (CAS 3488-90-2)
- Amylmetacresol EP Impurity F (CAS 150033-77-5)
- Amylmetacresol EP Impurity I (CAS 173851-73-5)
- Amylmetacresol EP Impurity J (CAS 10415-86-8)
- Amylmetacresol (CAS 1300-94-3)
- Amylmetacresol EP Impurity A (CAS 876473-73-3)
- Amylmetacresol Impurity 17 (CAS 1823068-39-8)
- Amylmetacresol EP Impurity C (CAS CATO-C4X-20253)
Recommended Standards
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- [1-[(Benzyloxy)methyl]cyclopropyl]methanol (CAS 177200-76-9)
- Lamotrigine EP Impurity E (CAS 50-45-3)
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- Pitavastatin Impurity 107 (CAS CATO-C4X-1037107)
- 3-methylazetidin-3-ol; trifluoroacetic acid (CAS 1104083-24-0)
- 1,1,1,2,2,5,5,6,6,6-Decafluoro-3-iodohexane (CAS 1980048-98-3)
- 4-Amino-5-benzoyl-2-(2,3-dimethylphenoxy)thiophene-3-carbonitrile (CAS 478248-33-8)
- Methyl 5-hydroxy-4-methylpicolinate (CAS 1211530-55-0)
- (E)-Pent-2-en-4-ynoic acid (CAS 68267-52-7)
- 4-(5-Isopropyl-2-methylphenoxy)aniline (CAS 946775-48-0)
- Antifreeze Polypeptide 6 (winter flounder) trifluoroacetate salt (CAS 122604-16-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com