3-(2-Bromo-1-hydroxyethyl)-5-chlorothiophene-2-sulfonamide CAS 174139-67-4
| CAS No. | 174139-67-4 |
| Molecular Formula | C6H7BrClNO3S2 |
| Molecular Weight | 320.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-(2-Bromo-1-hydroxyethyl)-5-chlorothiophene-2-sulfonamide (CAS 174139-67-4), a certified reference material (molecular formula C6H7BrClNO3S2, MW 320.61 g/mol) for analytical method development and quality control.
3-(2-Bromo-1-hydroxyethyl)-5-chlorothiophene-2-sulfonamide (C6H7BrClNO3S2) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2-Bromo-1-hydroxyethyl)-5-chlorothiophene-2-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H7BrClNO3S2 |
| Molecular Weight | 320.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2006 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Bromo Standards
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- Ethyl 2-bromo-4-chlorothieno[2,3-b]pyridine-5-carboxylate (CAS 1370619-77-4)
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Recommended Standards
- tert-Butyl (2-bromo-5-chloro-4-methylphenyl)carbamate (CAS 1564685-57-9)
- tert-Butyl N-(4-bromo-3-chlorophenyl)-N-methylcarbamate (CAS 1881288-49-8)
- tert-Butyl (4-bromo-3-chloro-2-methylphenyl)carbamate (CAS 1881328-92-2)
- (3-Bromo-6-chloro-2-fluorophenyl)(piperidin-1-yl)methanone (CAS 2504203-91-0)
- 2-(2,3-Dimethylpiperidin-1-yl)isonicotinic acid (CAS 1459166-71-2)
- 2',7'-Dichloro-3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxylic acid (CAS 144316-86-9)
- N-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-4-methoxyaniline (CAS 62001-34-7)
- 1-(4-Chlorobenzyl)-2-(chloromethyl)-1H-imidazole hydrochloride (CAS 655235-85-1)
- N-(2-Chlorophenyl)-5-methylisoxazole-4-carboxamide (CAS 61643-15-0)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(furan-3-yl)thiazol-5-yl)boronate (CAS 2223030-77-9)
- 3-(1-Methyl-1H-pyrrol-2-yl)[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid (CAS 1353504-92-3)
- (S)-2-acetamido-3-(3-hydroxyphenyl)propanoic acid (CAS 64325-07-1)
- 2,4-Dichloro-3-(difluoromethoxy)benzylamine (CAS 1806350-32-2)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
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