6-tert-Butyldimethylsilyl-4'-hydroxy Raloxifene CAS 174264-47-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-tert-Butyldimethylsilyl-4'-hydroxy Raloxifene.

CATO supplies 6-tert-Butyldimethylsilyl-4'-hydroxy Raloxifene (CAS 174264-47-2), a certified reference material (molecular formula C34H41NO4SSi, MW 587.84 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 6-tert-Butyldimethylsilyl-4'-hydroxy Raloxifene is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 587.84 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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