4-Chloro-8H-pyrrolo[3,2-g]quinazoline CAS 174709-48-9
| CAS No. | 174709-48-9 |
| Molecular Formula | C10H6ClN3 |
| Molecular Weight | 203.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-8H-pyrrolo[3,2-g]quinazoline.
4-Chloro-8H-pyrrolo[3,2-g]quinazoline (CAS 174709-48-9), molecular formula C10H6ClN3 and molecular weight 203.63 g/mol, is a CATO reference standard with documented purity and traceability.
4-Chloro-8H-pyrrolo[3,2-g]quinazoline (C10H6ClN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-8H-pyrrolo[3,2-g]quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6ClN3 |
| Molecular Weight | 203.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2006 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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- 5-chloro-1-phenyl-1H-pyrazole-4-carbonitrile (CAS 1050619-81-2)
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Recommended Standards
- methyl 2-[4-(2-chloroethyl)-1H-1,2,3-triazol-1-yl]acetate (CAS 1423025-47-1)
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- 4-(3-(Chloromethyl)-1,2,4-oxadiazol-5-yl)morpholine (CAS 1393558-45-6)
- Ethyl 2-(3-chloro-1H-1,2,4-triazol-1-yl)propanoate (CAS 1823967-22-1)
- (2E)-1-(3,4-Dichlorophenyl)-3-(4-ethylphenyl)prop-2-en-1-one (CAS 1354942-02-1)
- Atrazine-Desethyl-Desisopropyl-2-Hydroxy (Ammeline) (CAS 645-92-1)
- 5-Hydroxy-1-methyl-2-(trifluoromethyl)-1h-indole-3-carboxylic acid (CAS 1181287-69-3)
- n-(2-Butoxyethyl)-2-chloroacetamide (CAS 1193387-64-2)
- 4-(2-Chloro-2,2-difluoroethyl)-1-(chloromethyl)pyrrolidin-2-one (CAS 1294001-05-0)
- 1-(4-Methyl-1H-pyrazol-3-yl)ethanone (CAS 68809-57-4)
- N-(4-phenylpiperidin-4-yl)acetamide (CAS 146396-04-5)
- (4S)-6-Chlorochromane-4-ylamine (CAS 1018978-87-4)
- 1,1,1,6,6,6-Hexafluorohexane (CAS 3834-39-7)
- Liraglutide Impurity 22 (CAS 536721-25-2)
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