Diphenhydramine EP Impurity A(Dimenhydrinate EP Impurity F) CAS 17471-10-2
| CAS No. | 17471-10-2 |
| Molecular Formula | C16H19NO |
| Molecular Weight | 241.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Diphenhydramine EP Impurity A(Dimenhydrinate EP Impurity F) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Diphenhydramine EP Impurity A(Dimenhydrinate EP Impurity F) (CAS 17471-10-2, C16H19NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Diphenhydramine EP Impurity A(Dimenhydrinate EP Impurity F) (C16H19NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C16H19NO |
| Molecular Weight | 241.33 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 1 |
Related Diphenhydramine Standards
- Diphenhydramine Impurity 9 (CAS 26926-47-6)
- Diphenhydramine (CAS 58-73-1)
- Diphenhydramine EP Impurity B (CAS 19804-27-4)
- Diphenhydramine impurity 14 (CAS CATO-C4X-142414)
- Diphenhydramine N-Oxide (CAS 3922-74-5)
- Diphenhydramine impurity 9 (CAS CATO-C4X-14249)
- Diphenhydramine impurity 17 (CAS 22808-17-9)
- Diphenhydramine impurity 18 (CAS 150556-79-9)
Recommended Standards
- Dorzolamide Impurity 7 (CAS CATO-C4X-12287)
- Propranolol impurity 46 (CAS CATO-C4X-151946)
- Mirabegron Impurity 25 (CAS CATO-C4X-103225)
- Propranolol Impurity 60 (CAS CATO-C4X-151960)
- Apremilast Impurity 86 (CAS 106860-70-2)
- Tizanidine EP Impurity E (CAS 30536-19-7)
- Oteseconazole Impurity 3 (CAS CATO-C4X-33373)
- N-(5-Methyl-1H-indazol-7-yl)acetamide (CAS 871886-57-6)
- 4-(4-Bromophenyl)-N-(4-nitrobenzylidene)thiazol-2-amine (CAS 331962-79-9)
- 2-Phenethyl-6-phenyl-2H-pyran-4(3H)-one (CAS 1092060-08-6)
- 2-Amino-1-(4-bromophenyl)propan-1-ol (CAS 792876-12-1)
- (4-Fluoro-2-(pentyloxy)phenyl)methanol (CAS 1443309-56-5)
- ZHC-116 Impurity 6 (CAS CATO-C4X-23886)
- C-Peptide (Proinsulin) (CAS 59112-80-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com