6-(4-Chlorophenyl)pyrimidine-2,4-diamine CAS 175137-09-4
| CAS No. | 175137-09-4 |
| Molecular Formula | C10H9ClN4 |
| Molecular Weight | 220.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
6-(4-Chlorophenyl)pyrimidine-2,4-diamine (CAS 175137-09-4) is a high-purity analytical reference standard with the molecular formula C10H9ClN4 and a molecular weight of 220.66 g/mol.
The molecular framework of 6-(4-Chlorophenyl)pyrimidine-2,4-diamine (C10H9ClN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 6-(4-Chlorophenyl)pyrimidine-2,4-diamine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H9ClN4 |
| Molecular Weight | 220.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chlorophenyl Standards
- 6-(3-Chlorophenyl)pyrimidine-2,4-diamine (CAS 1251025-80-5)
- 5-(2-Chlorophenyl)pyrimidine-2,4-diamine (CAS 130801-37-5)
- 5-(4-Chlorophenyl)pyrimidine-2,4-diamine (CAS 17039-14-4)
- 4-(4-Chlorophenyl)-2-hydrazinylpyrimidine (CAS 932240-84-1)
- 5-(4-Chlorophenyl)-1-(prop-2-en-1-yl)-1H-1,2,3,4-tetrazole (CAS 303144-89-0)
- 1-(4-Chlorophenyl)-5-oxopyrrolidine-3-carbonitrile (CAS 1017458-43-3)
- 1-(2-chlorophenyl)-3-methyl-1H-pyrazole-4-carbaldehyde (CAS 1046784-68-2)
- 3-(2-Chlorophenyl)-1-methyl-1h-pyrazole-4-carbaldehyde (CAS 1152508-67-2)
Recommended Standards
- 5-Chlorothieno[2,3-d][1,2,3]thiadiazole-6-carboxylic acid (CAS 192878-32-3)
- 5-Chloro-3-(4,5-dihydro-1H-imidazol-2-yl)-1H-indazole (CAS 1649964-23-7)
- 4-chloro-N-methyl-6-phenyl-1,3,5-triazin-2(1H)-imine (CAS 1973-03-1)
- 5-chloro-7-methyl-1H-pyrazolo[4,3-d]pyrimidine-3-carboxylic acid (CAS 1511590-31-0)
- 4-Fluoro-3-(3-fluoropyridin-4-yl)aniline (CAS 462652-33-1)
- 5-Amino-4'-fluoro-1,6-dihydro-[1,1'-biphenyl]-3(2H)-one (CAS 604000-06-8)
- Methyl 2-(2,5-dimethylfuran-3-carboxamido)benzoate (CAS 179757-96-1)
- Cefpodoxime Impurity 47 (CAS CATO-C4X-157947)
- n,n-Diethyl-4-(2-nitroethyl)aniline (CAS 1824264-08-5)
- (2S,3R,5S,6R)-2-(5-((E)-3,5-dihydroxystyryl)-2-methoxyphenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS CATO-C3D-262406)
- 2-Chloro-6-methylthiazolo[4,5-b]pyridine (CAS 960535-45-9)
- 5-Bromo-4-(4-bromo-1h-pyrazol-1-yl)pyrimidine (CAS 1501562-91-9)
- 3-(3-(4-Phenylpiperazin-1-yl)propyl)quinazoline-2,4(1H,3H)-dione (CAS 2208-51-7)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
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