3-(3-(4-Phenylpiperazin-1-yl)propyl)quinazoline-2,4(1H,3H)-dione CAS 2208-51-7
| CAS No. | 2208-51-7 |
| Molecular Formula | C21H24N4O2 |
| Molecular Weight | 364.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-(3-(4-Phenylpiperazin-1-yl)propyl)quinazoline-2,4(1H,3H)-dione (CAS 2208-51-7), molecular formula C21H24N4O2 and molecular weight 364.44 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(3-(4-Phenylpiperazin-1-yl)propyl)quinazoline-2,4(1H,3H)-dione (C21H24N4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 3-(3-(4-Phenylpiperazin-1-yl)propyl)quinazoline-2,4(1H,3H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H24N4O2 |
| Molecular Weight | 364.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 4 |
Related Phenylpiperazin Standards
- 1-(4-Phenylpiperazin-1-yl)-2-(3-(trifluoromethyl)phenoxy)ethan-1-one (CAS 866153-13-1)
- 2-(4-Phenylpiperazin-1-yl)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 329080-47-9)
- 2-(4-Phenylpiperazin-1-yl)-N-(4-(trifluoromethyl)phenyl)acetamide (CAS 720667-94-7)
- 2-((4-Phenylpiperazin-1-yl)methyl)-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one (CAS 139047-55-5)
- N-(3-(4-Phenylpiperazin-1-yl)propyl)-2-(o-tolyloxy)acetamide (CAS 1049375-34-9)
- n-(4-((4-Phenylpiperazin-1-yl)sulfonyl)phenyl)acetamide (CAS 321531-92-4)
- 1-Methyl-4-{5-[(4-phenylpiperazin-1-yl)methyl]-1,3-thiazol-2-yl}piperazine (CAS 478079-09-3)
- 1-Phenyl-4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 393845-64-2)
Recommended Standards
- 3-(2-Ethoxyphenyl)-2-(piperazin-1-ylmethyl)quinazolin-4(3H)-one (CAS 903499-49-0)
- 3-(4,5-Dimethylbenzo[h][1,6]naphthyridin-2-yl)-2-methylquinolin-4-amine (CAS 71993-16-3)
- 2-Amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-(piperidin-4-yl)nicotinonitrile (CAS 406208-42-2)
- 3-(Anthracen-9-yl)-2-(m-tolyl)isoxazolidine-4-carbonitrile (CAS 477565-47-2)
- 1,3-Diaminotetrafluorobenzene (CAS 1198-63-6)
- 2-Methoxy-5-(((1-phenylethyl)amino)methyl)phenol (CAS 680185-58-4)
- (S)-1-(m-tolyl)propan-1-amine (CAS 1212973-31-3)
- Dimethyl 1-(2,3-dimethylphenyl)-1H-pyrazole-3,4-dicarboxylate (CAS 618069-97-9)
- 4-Amino-2-ethylpyrimidine-5-carbonitrile (CAS 76574-45-3)
- Methyl 3-(3-benzoylthioureido)-4-methylthiophene-2-carboxylate (CAS 1023805-51-7)
- (7R,8R)-2-Amino-7,8-dimethyl-7,8-dihydro-5H-pyrano[4,3-b]pyridin-5-one (CAS 2673370-43-7)
- 2,5-Difluoro-3-(trifluoromethoxy)benzodifluoride (CAS 1803871-91-1)
- 2-Chloro-5-methylpyridine-3-carbonyl chloride (CAS 1088496-56-3)
- Exenatide (CAS 141758-74-9)
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