Methyl 2-hydrazinyl-4-(trifluoromethyl)pyrimidine-5-carboxylate CAS 175137-28-7
| CAS No. | 175137-28-7 |
| Molecular Formula | C7H7F3N4O2 |
| Molecular Weight | 236.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 236.15 g/mol gives Methyl 2-hydrazinyl-4-(trifluoromethyl)pyrimidine-5-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 2-hydrazinyl-4-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 175137-28-7) is a high-purity analytical reference standard with the molecular formula C7H7F3N4O2 and a molecular weight of 236.15 g/mol.
The molecular framework of Methyl 2-hydrazinyl-4-(trifluoromethyl)pyrimidine-5-carboxylate (C7H7F3N4O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 2-hydrazinyl-4-(trifluoromethyl)pyrimidine-5-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7F3N4O2 |
| Molecular Weight | 236.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Methyl Standards
- 2-Hydrazinyl-4-(2-nitrophenyl)thiazole (CAS 886495-36-9)
- 2-Hydrazinyl-4-(4-nitrophenyl)thiazole (CAS 26049-70-7)
- 2-Hydrazinyl-4-(naphthalen-2-yl)pyrimidine (CAS 932240-75-0)
- 2-Hydrazinyl-5-iodopyrimidine (CAS 63558-64-5)
- 3-Hydrazinyl-6-iodopyridazine (CAS 399044-18-9)
- 2-Hydrazinyl-4-(4-methoxy-3-methylphenyl)thiazole (CAS 886494-19-5)
- 2-Hydrazinyl-4-(4-methoxyphenyl)-5-methylthiazole (CAS 886494-21-9)
- 8-Hydrazinyl-3-phenylcyclohepta[b]pyrrole (CAS 63725-20-2)
Recommended Standards
- 2-Methyl-6-(2,2,2-trifluoroethoxy)pyrimidine-4-carboxylic acid (CAS 1710695-95-6)
- 2-(3-Methyl-6-oxo-5-(trifluoromethyl)pyridazin-1(6H)-yl)acetic acid (CAS 1823265-20-8)
- 4-Nitro-3-(3,3,3-trifluoropropoxy)pyridine (CAS 1707602-41-2)
- Ethyl 6-oxo-4-(trifluoromethyl)-1,6-dihydropyridazine-3-carboxylate (CAS 184956-73-8)
- Tert-butyl (2R,4S)-2-(aminomethyl)-4-(trifluoromethyl)pyrrolidine-1-carboxylate (CAS 2166205-93-0)
- Cyclopropyl(3-(pyrrolidin-1-ylmethyl)phenyl)methanone (CAS 898770-94-0)
- 2-(2-Fluoro-6-isopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2098215-62-2)
- N-(5-nitro-1,3-thiazol-2-yl)formamide (CAS 500-08-3)
- Bendamustine Impurity 26 (CAS 2489521-68-6)
- Methyl 4-chloro-2-iodo-6-methylbenzoate (CAS 1078721-72-8)
- 1-{4-[4-(3-Pyrrolidinyloxy)phenyl]-1-piperazinyl}-1-ethanone 4135AF 946760-59-4 C16H23N3O2 (CAS 946760-59-4)
- 4,6-Dichloro-2,5-dimethylpyrimidine (CAS 1780-33-2)
- N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(2-(allylamino)ethyl)-L-serine (CAS CATO-CIM-105658)
- Dulaglutide (CAS 923950-08-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com