2-(Thiophen-2-ylsulfonyl)acetonitrile CAS 175137-62-9

Description

Compared with other compounds in its class, the molecular weight of 187.24 g/mol gives 2-(Thiophen-2-ylsulfonyl)acetonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(Thiophen-2-ylsulfonyl)acetonitrile (CAS 175137-62-9) is a high-purity analytical reference standard with the molecular formula C6H5NO2S2 and a molecular weight of 187.24 g/mol.

The molecular framework of 2-(Thiophen-2-ylsulfonyl)acetonitrile (C6H5NO2S2) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
• 130,000+ catalog items in stock, COA supplied with every batch
• Worldwide shipping with full export documentation (HS code guidance available)
• Technical support: +86 18665070610 / Nicole.chen@cato-chem.com