2-((4-Ethoxyphenyl)sulfonamido)benzoic acid CAS 327092-93-3
| CAS No. | 327092-93-3 |
| Molecular Formula | C15H15NO5S |
| Molecular Weight | 321.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-((4-Ethoxyphenyl)sulfonamido)benzoic acid (CAS 327092-93-3) is a high-purity analytical reference standard with the molecular formula C15H15NO5S and a molecular weight of 321.35 g/mol.
The molecular framework of 2-((4-Ethoxyphenyl)sulfonamido)benzoic acid (C15H15NO5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H15NO5S |
| Molecular Weight | 321.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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- Ethyl 4-((4-ethoxyphenyl)carbamoyl)piperazine-1-carboxylate (CAS 1022100-71-5)
- 2-((4-Ethoxyphenyl)amino)-N-(isoquinolin-6-yl)acetamide (CAS 920513-46-8)
- 2-(2-Ethoxyphenyl)-6,8-dimethylquinoline-4-carboxylic acid (CAS 897554-46-0)
- 2-(3-Ethoxyphenyl)-6,8-dimethylquinoline-4-carboxylic acid (CAS 588674-01-5)
- 2-(3-Ethoxyphenyl)-7,8-dimethylquinoline-4-carboxylic acid (CAS 895967-47-2)
- 2-(4-Ethoxyphenyl)-3,6-dimethylquinoline-4-carboxylic acid (CAS 438218-83-8)
Recommended Standards
- 1-Amino-4-(thiazol-2-ylamino)anthracene-9,10-dione (CAS 62593-03-7)
- 2-(2-(((3-Phenyl-1,2,4-oxadiazol-5-yl)methyl)thio)propanamido)acetic acid (CAS 71484-14-5)
- [(Methylsulfonyl)(2-phenoxyphenyl)amino]-acetic acid (CAS 952901-05-2)
- 2-(2-(2-(1-(4-Methoxyphenyl)ethylidene)hydrazinyl)-4-oxo-4,5-dihydrothiazol-5-yl)acetic acid (CAS 78381-99-4)
- N-(3-Amino-4-chlorophenyl)-2-(2-methylphenoxy)-propanamide (CAS 1020054-69-6)
- 2-(4-(Aminomethyl)-1,1-dioxidotetrahydro-2H-thiopyran-4-yl)acetic acid hydrochloride (CAS 1803591-43-6)
- 7-(4-Bromophenyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 160290-40-4)
- 1-(4-(4-(1-Methyl-3-(thiophen-2-yl)-1H-pyrazole-5-carbonyl)piperazin-1-yl)phenyl)ethan-1-one (CAS 1219906-08-7)
- 3-(Boc-aminomethyl)cyclohexylamine (CAS 347184-70-7)
- 5-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-1,3,4-thiadiazole-2-thiol (CAS 742094-74-2)
- Fmoc-Aph(tBuCbm)-OH (CAS 1998216-17-3)
- 2,3-Bis(4-methoxyphenyl)benzofuran (CAS 5782-17-2)
- 2-(But-3-yn-1-ylamino)isonicotinic acid (CAS 1409743-84-5)
- Semaglutide impurity 86 (CAS CATO-C4X-222686)
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