5-((5-(Trifluoromethyl)pyridin-2-yl)sulfonyl)thiophene-2-sulfonyl chloride CAS 175202-87-6
| CAS No. | 175202-87-6 |
| Molecular Formula | C10H5ClF3NO4S3 |
| Molecular Weight | 391.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-((5-(Trifluoromethyl)pyridin-2-yl)sulfonyl)thiophene-2-sulfonyl chloride is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-((5-(Trifluoromethyl)pyridin-2-yl)sulfonyl)thiophene-2-sulfonyl chloride (CAS 175202-87-6) is a high-purity analytical reference standard with the molecular formula C10H5ClF3NO4S3 and a molecular weight of 391.79 g/mol.
5-((5-(Trifluoromethyl)pyridin-2-yl)sulfonyl)thiophene-2-sulfonyl chloride (C10H5ClF3NO4S3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H5ClF3NO4S3 |
| Molecular Weight | 391.79 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 3 |
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Recommended Standards
- Ethyl 1-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate (CAS 338965-01-8)
- 2-((4-Chlorobenzyl)sulfonyl)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 339107-23-2)
- CTEP (RO4956371) (CAS 871362-31-1)
- Ethyl 3-(2-chloro-6-fluorophenyl)-2-(1-(6-fluoropyridin-2-yl)-1H-pyrazol-5-yl)propanoate (CAS 477709-64-1)
- Ethyl 3-(((benzyloxy)carbonyl)(2-methoxy-2-oxoethyl)amino)propanoate (CAS 1245646-09-6)
- N-(3-cyano-5-phenylfuran-2-yl)benzamide (CAS 98061-62-2)
- 2,4-Dichloro-1-(3-chloropropyl)benzene (CAS 72506-10-6)
- 4-((Trifluoromethyl)thio)benzene-1,2-diamine dihydrochloride (CAS 1313012-28-0)
- (R)-1-(3-(1,1-Difluoro-2-methoxyethyl)-2-methyl-5-nitrophenyl)ethanamine hydrochloride (CAS 2883761-52-0)
- Ethyl 7-bromo-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 208580-23-8)
- Methyl 2-(2-Chloropyridin-4-yl)acetate (CAS 884600-82-2)
- 2-(2-Fluoro-6-isopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2098215-62-2)
- 2-Hydrazinyl-1-phenylethan-1-ol (CAS 4397-11-9)
- Peptide Impurity 40 (CAS CATO-CPTD788840)
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