4-(1-Piperazinyl)-2-(trifluoromethyl)quinoline CAS 175203-79-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(1-Piperazinyl)-2-(trifluoromethyl)quinoline.

4-(1-Piperazinyl)-2-(trifluoromethyl)quinoline (CAS 175203-79-9) is a high-purity analytical reference standard with the molecular formula C14H14F3N3 and a molecular weight of 281.28 g/mol.

Based on its molecular formula C14H14F3N3, 4-(1-Piperazinyl)-2-(trifluoromethyl)quinoline contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 281.28 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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