6-(Trifluoromethoxy)quinolin-4-ol CAS 175203-87-9
| CAS No. | 175203-87-9 |
| Molecular Formula | C10H6F3NO2 |
| Molecular Weight | 229.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-(Trifluoromethoxy)quinolin-4-ol (CAS 175203-87-9) is a high-purity analytical reference standard with the molecular formula C10H6F3NO2 and a molecular weight of 229.16 g/mol.
The molecular framework of 6-(Trifluoromethoxy)quinolin-4-ol (C10H6F3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-(Trifluoromethoxy)quinolin-4-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6F3NO2 |
| Molecular Weight | 229.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethoxy Standards
- 6-(Trifluoromethoxy)quinolin-4(1H)-one (CAS 1071540-62-9)
- 7-(Trifluoromethoxy)isoquinolin-1(2H)-one (CAS 1184917-30-3)
- 5-(Trifluoromethoxy)-1H-indole-2-carbaldehyde (CAS 1219928-85-4)
- 122454-46-0 3-Oxo-3-[4-(trifluoromethoxy)phenyl]propionitrile 3-oxo-3-[4-(trifluoromethoxy)phenyl]propanenitrile 4-(Trifluoromethoxy)benzoyl acetonitrile 4-(Trifluoromethoxy)benzoylacetonitrile 97% (CAS 122454-46-0)
- 5-[4-(Trifluoromethoxy)phenyl]-1,3-oxazole (CAS 1227954-44-0)
- 7-(Trifluoromethoxy)quinolin-2(1H)-one (CAS 1239461-99-4)
- 8-(Trifluoromethoxy)quinolin-2(1H)-one (CAS 1261626-98-5)
- 5-(Trifluoromethoxy)quinolin-4-ol (CAS 1261749-07-8)
Recommended Standards
- 6-(Trifluoromethyl)-5H-[1,3]dioxolo[4,5-f]indole (CAS 174907-36-9)
- 2-(Trifluoromethyl)-1H-indole-5-carboxylic acid (CAS 1784332-77-9)
- 7-(Trifluoromethyl)-1H-indole-2-carboxylic acid (CAS 172216-98-7)
- 1-(7-(Trifluoromethyl)benzo[d]oxazol-2-yl)ethanone (CAS 1804213-91-9)
- 1-Methylcyclohexan-1-amine hydrochloride (CAS 89854-70-6)
- WST-3 (CAS 515111-36-1)
- (S)-1-Benzyl-2-phenylpiperidin-4-one (CAS 1346773-44-1)
- Benzyl 2-(6-chloro-4-methylpyridin-3-yl)piperidine-1-carboxylate (CAS 1352495-24-9)
- Benzenesulfonamide, 4-bromo-N-(3-methoxyphenyl)- (CAS 349404-74-6)
- 2-(4-Bromophenyl)-6-methylpyrimidin-4(1H)-one (CAS 180606-52-4)
- (7-Amino-3-((tetrahydrofuran-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)methanol (CAS 1206970-17-3)
- 2,2,2-Trifluoroacetic acid compound with 4-amino-2-oxabicyclo[2.1.1]Hexane-1-carboxylic acid (1:1) (CAS 2309465-00-5)
- (4-Chloro-2-fluorobenzyl)(3-chlorophenyl)sulfane (CAS 1443327-65-8)
- Semaglutide Impurity 124 (CAS CATO-C4X-2226124)
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