6-Chloro-7-hydroxy-4-(methoxymethyl)-2H-chromen-2-one CAS 175205-11-5

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

6-Chloro-7-hydroxy-4-(methoxymethyl)-2H-chromen-2-one (CAS 175205-11-5), molecular formula C11H9ClO4 and molecular weight 240.64 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 6-Chloro-7-hydroxy-4-(methoxymethyl)-2H-chromen-2-one (C11H9ClO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), 6-Chloro-7-hydroxy-4-(methoxymethyl)-2H-chromen-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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