2-Chloro-4-(trifluoromethyl)phenylisothiocyanate CAS 175205-38-6
| CAS No. | 175205-38-6 |
| Molecular Formula | C8H3ClF3NS |
| Molecular Weight | 237.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-4-(trifluoromethyl)phenylisothiocyanate (C8H3ClF3NS) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Chloro-4-(trifluoromethyl)phenylisothiocyanate (CAS 175205-38-6) is a high-purity analytical reference standard with the molecular formula C8H3ClF3NS and a molecular weight of 237.63 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-4-(trifluoromethyl)phenylisothiocyanate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H3ClF3NS |
| Molecular Weight | 237.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-6-(trifluoromethylthio)benzonitrile (CAS 1159512-54-5)
- 2-Chloro-7-(trifluoromethyl)benzo[d]thiazole (CAS 1175277-66-3)
- 5-Chloro-2-(trifluoromethyl)benzo[d]thiazole (CAS 1188091-26-0)
- 4-Chloro-2-(trifluoromethyl)benzo[d]thiazole (CAS 1188144-87-7)
- 7-Chloro-2-(trifluoromethyl)benzo[d]thiazole (CAS 1188167-35-2)
- 2-Chloro-6-trifluoromethylbenzothiazole (CAS 159870-86-7)
- 2-Chloro-4-(trifluoromethyl)benzo[d]thiazole (CAS 898748-15-7)
- 2-Chloro-4-isothiocyanato-1-(trifluoromethyl)benzene (CAS 30613-71-9)
Recommended Standards
- 2-(Chloromethyl)-4-(difluoromethyl)-3,6-dimethoxypyridine (CAS 1805325-11-4)
- (S)-3-(Trifluoromethyl)pyrrolidine-1-sulfonyl chloride (CAS 1446526-76-6)
- 2-(Chloromethyl)-5-(difluoromethyl)-3,6-dimethoxypyridine (CAS 1806821-33-9)
- 3-(Trifluoromethyl)pyrrolidine-1-sulfonyl chloride (CAS 1446526-74-4)
- Iron(II) dodecanoate (CAS 21248-71-5)
- {2-[(2-methylphenyl)amino]-1,3-thiazol-4-yl}methanol hydrochloride (CAS 1170156-81-6)
- (R)-2-Acetamido-3-(4-iodophenyl)propanoic acid (CAS 201351-59-9)
- 2-Cyclopropoxy-N1,N4-dimethylbenzene-1,4-diamine (CAS 1243382-72-0)
- Diethyl 3-Bromobenzylphosphonate (CAS 128833-03-4)
- n-[(pyrazin-2-yl)methylidene]hydroxylamine (CAS 1193-98-2)
- tert-Butyl 3-(((S)-2-amino-N-methylpropanamido)methyl)pyrrolidine-1-carboxylate (CAS 1354028-70-8)
- 4-(Cyclobutylmethyl)tetrahydro-2h-thiopyran-4-carboxylic acid 1,1-dioxide (CAS 2090429-74-4)
- 2-Chloro-3-(2-oxopyrrolidin-1-yl)benzene-1-sulfonyl chloride (CAS 1184297-87-7)
- Peptide Impurity 15 (CAS 1227750-69-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com