5-Nitro-2-(4-(trifluoromethyl)piperidin-1-yl)pyridine CAS 175277-61-9
| CAS No. | 175277-61-9 |
| Molecular Formula | C11H12F3N3O2 |
| Molecular Weight | 275.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Nitro-2-(4-(trifluoromethyl)piperidin-1-yl)pyridine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Nitro-2-(4-(trifluoromethyl)piperidin-1-yl)pyridine (CAS 175277-61-9), molecular formula C11H12F3N3O2 and molecular weight 275.23 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 5-Nitro-2-(4-(trifluoromethyl)piperidin-1-yl)pyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 275.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Nitro-2-(4-(trifluoromethyl)piperidin-1-yl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12F3N3O2 |
| Molecular Weight | 275.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Nitro Standards
- 1-(4-Nitro-3-(trifluoromethyl)phenyl)piperazine (CAS 153204-82-1)
- 1-(4-Nitro-2-(trifluoromethyl)phenyl)piperazine (CAS 381242-61-1)
- 1-[2-Nitro-4-(trifluoromethyl)phenyl]piperazine (CAS 58315-38-1)
- 4-Nitro-2-(thiazol-2-yl)isoindoline-1,3-dione (CAS 16258-96-1)
- 2-[(2-nitro-4-sulfamoylphenyl)amino]acetic acid (CAS 848658-84-4)
- 3-Methyl-4-nitro-5-(4-nitrostyryl)isoxazole (CAS 78080-53-2)
- 1-(4-Nitro-benzyl)-1H-pyrazole-4-carboxylic acid ethyl ester (CAS 1197233-25-2)
- 2-Methyl-6-nitro-2-(phenoxymethyl)-2,3-dihydroimidazo[2,1-b]oxazole (CAS 923013-53-0)
Recommended Standards
- 4-((4-Fluorobenzyl)oxy)-3-nitrobenzaldehyde (CAS 175136-18-2)
- Benzyl 2-fluoro-6-nitrobenzoate (CAS 1820604-19-0)
- 1-(2-Methyl-6-(trifluoromethyl)pyrimidin-4-yl)pyrrolidine-3-carboxylic acid (CAS 1707372-78-8)
- Methyl 4-(3-fluoro-5-nitrophenyl)benzoate (CAS 1820641-03-9)
- 3-(4-Bromophenyl)-1-(3-fluorophenyl)propan-1-one (CAS 898761-37-0)
- n-(Tert-butyl)but-3-yn-1-amine (CAS 111462-95-4)
- 4-Hydrazinyl-1,6-dimethyl-1h-pyrazolo[3,4-d]pyrimidine (CAS 6288-92-2)
- 7-Bromo-2-(chloromethyl)-1-methyl-1H-imidazo[4,5-c]pyridine (CAS 1171920-75-4)
- Atrasentan Impurity 101 (CAS 1059052-04-8)
- 2-(1,3-Diethoxy-1,3-dioxopropan-2-yl)nicotinic acid (CAS 58380-23-7)
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- N-(2-ethoxybenzyl)-N-(4H-1,2,4-triazol-4-yl)amine (CAS 445413-73-0)
- Thymidine 5'-diphosphoric acid trisodium salt (CAS 95648-78-5)
- D-Phe6-Tirzepatide (CAS CATO-CPTD788925)
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