2-((2,4-Difluorophenyl)thio)acetonitrile CAS 175277-63-1
| CAS No. | 175277-63-1 |
| Molecular Formula | C8H5F2NS |
| Molecular Weight | 185.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 185.19 g/mol gives 2-((2,4-Difluorophenyl)thio)acetonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-((2,4-Difluorophenyl)thio)acetonitrile (CAS 175277-63-1), a certified reference material (molecular formula C8H5F2NS, MW 185.19 g/mol) for analytical method development and quality control.
The molecular framework of 2-((2,4-Difluorophenyl)thio)acetonitrile (C8H5F2NS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-((2,4-Difluorophenyl)thio)acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5F2NS |
| Molecular Weight | 185.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Difluorophenyl Standards
- (3,4-Difluorophenyl)isobutylamine (CAS 1019621-65-8)
- (3,5-Difluorophenyl)isobutylamine (CAS 1020962-86-0)
- 1-(3,4-Difluorophenyl)butan-1-amine (CAS 1020970-03-9)
- 1-(2,4-Difluorophenyl)-2-methylpropan-1-amine (CAS 1021001-13-7)
- 1-(3,4-difluorophenyl)-2-methylpropan-1-amine (CAS 1021031-68-4)
- 1-(2,4-difluorophenyl)butan-1-amine (CAS 1021033-54-4)
- [(2,4-Difluorophenyl)methyl](propan-2-yl)amine (CAS 1021091-66-6)
- 1-(2,5-Difluorophenyl)butan-1-amine (CAS 1021114-10-2)
Recommended Standards
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- 4-(5-amino-4H-1,2,4-triazol-3-yl)benzonitrile (CAS 168893-26-3)
- 4-Cyano-2,5-difluorothioanisole (CAS 1804896-75-0)
- 4-(Chloromethyl)-1-ethoxy-4-methylhexane (CAS 1463472-56-1)
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- (4-((1-(Tert-butoxycarbonyl)piperidin-4-yl)oxy)-3-methoxyphenyl)boronic acid (CAS 1072946-30-5)
- tert-Butyl 3-(hydroxymethyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazine-7-carboxylate (CAS 1314391-41-7)
- Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate (CAS 1256360-05-0)
- ethyl 2-[2-(2-hydroxyethyl)phenyl]acetate (CAS 63969-86-8)
- 1-(4-Hydroxy-1,5-dimethyl-1H-pyrazol-3-yl)ethanone (CAS 85985-64-4)
- 2,3-Difluoro-6-methylbenzotrifluoride (CAS 1806332-84-2)
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