2-(Trifluoromethoxy)iodobenzene CAS 175278-00-9
| CAS No. | 175278-00-9 |
| Molecular Formula | C7H4F3IO |
| Molecular Weight | 288.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Trifluoromethoxy)iodobenzene.
2-(Trifluoromethoxy)iodobenzene (CAS 175278-00-9), molecular formula C7H4F3IO and molecular weight 288.01 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C7H4F3IO, 2-(Trifluoromethoxy)iodobenzene contains a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 288.01 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Trifluoromethoxy)iodobenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4F3IO |
| Molecular Weight | 288.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F/I-containing |
Related Trifluoromethoxy Standards
- 3-(Trifluoromethoxy)iodobenzene (CAS 198206-33-6)
- 3-(4-(Trifluoromethoxy)phenyl)-1,2,4-oxadiazole-5-carbohydrazide (CAS 883028-82-8)
- 5-[4-(trifluoromethoxy)phenyl]thiophene-2-carboxylic acid (CAS 1039859-73-8)
- 5-[3-(trifluoromethoxy)phenyl]thiophene-2-carboxylic acid (CAS 1261747-75-4)
- 1-[2-(4-Trifluoromethoxy-phenyl)-thiazol-4-yl]-ethanone (CAS 265126-59-8)
- (3E)-3-(1-{[4-(trifluoromethoxy)phenyl]amino}ethylidene)oxolan-2-one (CAS 866132-73-2)
- 5-Methyl-1-[3-(trifluoromethoxy)phenyl]-1H-1,2,3-triazole-4-carboxylic acid (CAS 1326837-94-8)
- 2-oxo-1-[3-(trifluoromethoxy)phenyl]pyrrolidine-3-carboxylic acid (CAS 1016508-24-9)
Recommended Standards
- 6-Iodo-2-trifluoromethylphenol (CAS 149209-48-3)
- 3-(Difluoromethyl)-4-fluoro-6-iodopyridin-2-amine (CAS 1804946-44-8)
- 5-Iodo-4-(trifluoromethyl)pyridin-2-amine (CAS 1321530-57-7)
- 6-(Difluoromethyl)-2-fluoro-3-iodopyridin-4-amine (CAS 1804946-67-5)
- 1-Bromo-N-(1-(2-methoxyacetyl)-1,2,3,4-tetrahydroquinolin-7-yl)methanesulfonamide (CAS 1172391-20-6)
- 5-Chloro-2-fluoroiodobenzene (CAS 116272-42-5)
- 6-Amino-4-(difluoromethyl)-5-(hydroxymethyl)pyridin-3-ol (CAS 1805208-17-6)
- n,n-Dimethyl-2-(((5-methylfuran-2-yl)methyl)amino)acetamide (CAS 1096273-36-7)
- 2-Methoxy-5-(prop-2-yn-1-yloxy)benzoic acid (CAS 85608-01-1)
- trans-4-((1-(3,4-Dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)amino)cyclohexan-1-ol (CAS 1420978-81-9)
- 1-(4-(5-Bromopyrazin-2-yl)piperidin-1-yl)-2,2-dimethylpropan-1-one (CAS 1316218-22-0)
- Pemafibrate Impurity 50 (CAS CATO-C4X-290350)
- 4-(4-methoxyphenyl)-4-phenylpiperidine hydrochloride (CAS 1170596-97-0)
- (Leu31,Pro34)-Peptide YY (human) trifluoroacetate salt (CAS 179986-95-9)
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