3-{4-[(4-Chlorophenyl)thio]-3-nitrophenyl}acrylic acid CAS 175278-52-1
| CAS No. | 175278-52-1 |
| Molecular Formula | C15H10ClNO4S |
| Molecular Weight | 335.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-{4-[(4-Chlorophenyl)thio]-3-nitrophenyl}acrylic acid.
3-{4-[(4-Chlorophenyl)thio]-3-nitrophenyl}acrylic acid (CAS 175278-52-1), molecular formula C15H10ClNO4S and molecular weight 335.76 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 3-{4-[(4-Chlorophenyl)thio]-3-nitrophenyl}acrylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 335.76 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-{4-[(4-Chlorophenyl)thio]-3-nitrophenyl}acrylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H10ClNO4S |
| Molecular Weight | 335.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 4-(4-Chlorophenyl)-2-((4-fluorobenzyl)amino)-4-oxobutanoic acid (CAS 1025762-54-2)
- 2-{[(4-chlorophenyl)methyl]amino}-4-(4-fluorophenyl)-4-oxobutanoic acid (CAS 1032129-83-1)
- (Z)-3-(2-((4-chlorophenyl)thio)-5-nitrophenyl)acrylic acid (CAS 175278-51-0)
- 2-(2-(4-Chlorophenyl)-2-oxoethyl)benzo[d]isothiazol-3(2H)-one 1,1-dioxide (CAS 41335-62-0)
- 1-(2-(4-Chlorophenyl)-2-oxoethyl)-N4,N5-dimethyl-1H-1,2,3-triazole-4,5-dicarboxamide (CAS 1351772-48-9)
- 2-{[4-(4-chlorophenyl)-5-(furan-2-yl)-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 893725-75-2)
- 4-(3-Chlorophenyl)-5-(ethoxycarbonyl)-2,6-dimethyl-1,4-dihydropyridine-3-carboxylic acid (CAS 148455-50-9)
- 5-(2-Chlorophenyl)-3-((naphthalen-2-yloxy)methyl)isoxazole (CAS 339019-76-0)
Recommended Standards
- 1-(4-Chloro-2-fluorophenyl)-4-(2-nitrophenyl)piperazine (CAS 2006276-87-3)
- 4-Chloro-3-(N-(3-ethynylphenyl)sulfamoyl)benzoic acid (CAS 1119216-64-6)
- 2-((4-Fluorobenzyl)amino)-2-oxoethyl 2-(4-chlorophenyl)acetate (CAS 757208-57-4)
- 3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-5-methylisothiazole-4-carbonitrile (CAS 338775-63-6)
- 3-Amino-6-(aminomethyl)-1,2,4-triazin-5(2H)-one acetate (CAS 1353100-80-7)
- 6-Chloro-1-(4-iodophenyl)hexan-1-one (CAS 898768-23-5)
- Coumarin-7-pinacolboronate (CAS 190788-61-5)
- Naphthalene-1,3,5-trisulfonic acid, sodium salt(1:1) (CAS 104768-26-5)
- (4-Chlorophenyl){[4-(piperidin-1-ylmethyl)-2-thienyl]methyl}amine (CAS 1243052-94-9)
- Apixaban Impurity 153 (CAS CATO-C4X-1088153)
- 5-(4-Bromo-2-fluorophenyl)pyrimidine (CAS 1088410-67-6)
- 3-(4-Iodophenyl)-1-isopropyl-1H-pyrazol-5-amine (CAS 1017781-38-2)
- 2,3,4-Trifluoro-6-(trifluoromethyl)pyridine (CAS 1214330-71-8)
- Semaglutide impurity 259 (CAS CATO-C4X-2226259)
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