5-(2-Chlorophenyl)-3-((naphthalen-2-yloxy)methyl)isoxazole CAS 339019-76-0
| CAS No. | 339019-76-0 |
| Molecular Formula | C20H14ClNO2 |
| Molecular Weight | 335.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 335.78 g/mol gives 5-(2-Chlorophenyl)-3-((naphthalen-2-yloxy)methyl)isoxazole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(2-Chlorophenyl)-3-((naphthalen-2-yloxy)methyl)isoxazole (CAS 339019-76-0) is a high-purity analytical reference standard with the molecular formula C20H14ClNO2 and a molecular weight of 335.78 g/mol.
Structurally, 5-(2-Chlorophenyl)-3-((naphthalen-2-yloxy)methyl)isoxazole (C20H14ClNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 335.78 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H14ClNO2 |
| Molecular Weight | 335.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 4-Chloro-2-(p-tolyl)quinoline-6-sulfonyl fluoride (CAS 31241-73-3)
- 4-(Tert-butyl)-N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)thiazol-2-amine (CAS 338409-42-0)
- 5-Chloro-2-methoxy-9-phenoxyacridine (CAS 94551-44-7)
- 4-(3-Chloro-4-fluorophenyl)-5-(4-methoxyphenyl)-4h-1,2,4-triazole-3-thiol (CAS 380349-22-4)
- 6-Chloro-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine (CAS 1823379-92-5)
- Methyl 3-(2,4-difluorophenyl)-3-methyloxirane-2-carboxylate (CAS 1467430-12-1)
- 5-(4-Bromophenyl)-1-methyl-1H-1,2,4-triazole-3-carboxylic acid (CAS 1373223-59-6)
- N, N-Bis(4-amino-2-methyl-6-quinolinyl) urea (CAS 3811-56-1)
- 5-ethyl-1-[4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxylic acid (CAS 1466051-04-6)
- (2-methoxyphenyl)(4-methoxyphenyl)methanamine hydrochloride (CAS 1423027-24-0)
- 2-(4-Hydroxyphenyl)-4H-chromen-4-one (CAS 4143-63-9)
- (S)-Methyl 2-amino-3-cyclopropylpropanoate (CAS 732231-41-3)
- (S)-Benzyl 3-(tosyloxy)piperidine-1-carboxylate (CAS 1354020-77-1)
- [3-31]-Semaglutide D (CAS C152H230N42O47)
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