methyl 5-chloro-1H-pyrrole-2-carboxylate CAS 1757-31-9
| CAS No. | 1757-31-9 |
| Molecular Formula | C6H6ClNO2 |
| Molecular Weight | 159.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
methyl 5-chloro-1H-pyrrole-2-carboxylate (CAS 1757-31-9) is a high-purity analytical reference standard with the molecular formula C6H6ClNO2 and a molecular weight of 159.57 g/mol.
methyl 5-chloro-1H-pyrrole-2-carboxylate (C6H6ClNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures methyl 5-chloro-1H-pyrrole-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNO2 |
| Molecular Weight | 159.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related methyl Standards
- 2-(4-Chloro-1H-pyrazol-1-yl)acetamide (CAS 1006506-31-5)
- 6-Chloro-4-methoxypyridine-2(1H)-one (CAS 108279-65-8)
- 3-Chloro-5-methoxypyridine 1-oxide (CAS 110038-48-7)
- 5-Chloro-1-methyl-1H-pyrazole-4-carboxamide (CAS 110763-18-3)
- Methyl 4-chloro-1H-pyrrole-2-carboxylate (CAS 1194-96-3)
- 2-Chloro-6-methoxypyridin-3-ol (CAS 1196145-59-1)
- 6-Chloro-2-methoxypyridin-3-ol (CAS 1196146-98-1)
- 4-Chloro-6-methoxypyridin-3-ol (CAS 1196152-16-5)
Recommended Standards
- N-(3-Chloro-1H-pyrazol-4-yl)acetamide (CAS 1704063-31-9)
- (5-Amino-2-chloropyrimidin-4-yl)methanol (CAS 1781006-96-9)
- 5-Amino-2-chloro-6-methylpyrimidin-4-ol (CAS 1691605-41-0)
- 1797131-45-3 3-Chloro-1-(1H-1,2,4-triazol-1-yl)-propan-2-one (CAS 1797131-45-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com