Glucose Impurity 40 CAS 175845-69-9
| CAS No. | 175845-69-9 |
| Molecular Formula | C14H25NO12 |
| Molecular Weight | 399.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Glucose Impurity 40 (C14H25NO12) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Glucose Impurity 40 (CAS 175845-69-9, C14H25NO12) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H25NO12 |
| Molecular Weight | 399.35 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2007 |
| Nitrogen Atoms | 1 |
Related Glucose Standards
- D-Glucose 2,3,4,5,6-Pentaacetate (CAS 3891-59-6)
- β-L-Glucose pentaacetate (CAS 66966-07-2)
- α-D-Glucose 1-Phosphate Dipotassium SaltDiscontinued See G596815 (CAS 6736-77-2)
- Glucose Impurity 37 (CAS 554-37-0)
- Glucose Impurity 36 (CAS 23363-08-8)
- Glucose Impurity 44 (CAS CATO-C4X-209544)
- Glucose - Impurity C (CAS 113158-51-3)
- α-D-Glucose 6-phosphate (CAS 15209-11-7)
Recommended Standards
- Nicardipine Impurity 29 (CAS CATO-C4X-171029)
- Glycine Impurity 5 (CAS CATO-C4X-33365)
- Nocardicin F (CAS 63598-46-9)
- Methyl 3,3-dimethoxy-2-[2-[[6-(trifluoromethyl)pyridin-2-yl]oxymethyl]phenyl]propanoate (CAS 1448851-52-2)
- Vortioxetine Impurity 90 (CAS 50606-33-2)
- Agomelatine Impurity N15 (CAS 1607465-48-4)
- Propranolol Impurity 30 (CAS 27827-19-6)
- 4-Methoxy-3-methyl-N-(2-(2-methylthiazol-4-yl)ethyl)benzenesulfonamide (CAS 863511-62-0)
- 2-Amino-3,6-dimethylpyridine (CAS 823-61-0)
- 1-(2-Ethoxyphenyl)-1H-pyrrole-2,5-dione (CAS 36817-57-9)
- tert-Butyl (1-(6-methoxy-2-(methylthio)pyrimidin-4-yl)piperidin-4-yl)carbamate (CAS 1353946-56-1)
- Ethyl 1-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine-4-carboxylate (CAS 1268692-87-0)
- Mianserin Impurity 101 (CAS CATO-C4X-1369101)
- Tirzepatide Impurity 16 (CAS CATO-C4X-324016)
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