Propranolol Impurity 30 CAS 27827-19-6
| CAS No. | 27827-19-6 |
| Molecular Formula | C16H21NO2 |
| Molecular Weight | 259.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Propranolol Impurity 30 (CAS 27827-19-6), a pharmacopoeial impurity reference standard (molecular formula C16H21NO2, MW 259.34 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Propranolol Impurity 30 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 259.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Propranolol Impurity 30 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H21NO2 |
| Molecular Weight | 259.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 1 |
Related Propranolol Standards
- (S)-Propranolol, 98% (CAS 4199-09-1)
- Propranolol Impurity 31 (CAS CATO-C4X-151931)
- Propranolol Impurity 49 (CAS CATO-C4X-151949)
- Propranolol Impurity 5 (CAS 2007-72-9)
- Propranolol Impurity 52 (CAS CATO-C4X-151952)
- Propranolol Impurity 54 (CAS CATO-C4X-151954)
- Propranolol (CAS 525-66-6)
- Propranolol Impurity 15 (CAS CATO-C4X-151915)
Recommended Standards
- Atropine Impurity 46 (CAS 1690-22-8)
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- Thioctic acid Impurity 19 (CAS 91140-37-3)
- Carbocisteine Impurity 28 (CAS CATO-C4X-201028)
- Butylphthalide Impurity N4 (CAS 168288-19-5)
- Ethyl (1r,4r)-4-(aminomethyl)cyclohexane-1-carboxylate (CAS 35879-53-9)
- BYS10- BP40 (CAS CATO-C3D-263282)
- 6,7-Dihydro-4H-thieno[3,2-c]pyran-4-carboxylic acid (CAS 1428233-08-2)
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- 1-Oxo-2-(3,4,5-trifluorophenyl)-1,2-dihydroisoquinoline-4-carboxylic acid (CAS 1383626-11-6)
- 1-(4-Biphenylyl)ethanol (CAS 3562-73-0)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com