2,3-Difluoro-4-hydroxybenzoic Acid CAS 175968-39-5
| CAS No. | 175968-39-5 |
| Molecular Formula | C7H4F2O3 |
| Molecular Weight | 174.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2,3-Difluoro-4-hydroxybenzoic Acid (CAS 175968-39-5), a certified reference material (molecular formula C7H4F2O3, MW 174.10 g/mol) for analytical method development and quality control.
The molecular framework of 2,3-Difluoro-4-hydroxybenzoic Acid (C7H4F2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,3-Difluoro-4-hydroxybenzoic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4F2O3 |
| Molecular Weight | 174.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 3,5-Difluoro-4-nitroaniline (CAS 122129-79-7)
- 2,4-Difluoro-5-nitroaniline (CAS 123344-02-5)
- 2,2-Difluoro-2-(pyrimidin-5-yl)acetic acid (CAS 1250738-18-1)
- 2,5-Difluoro-4-hydroxybenzoic acid (CAS 146781-23-9)
- 2,5-Difluoro-4-nitroaniline (CAS 1542-36-5)
- 2,5-Difluoro-3-nitroaniline (CAS 1699538-79-8)
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Recommended Standards
- 2-(Difluoromethyl)-5-nitropyridine (CAS 1646152-46-6)
- 4-(Difluoromethyl)pyrimidine-2-carboxylic acid (CAS 1782555-45-6)
- 2,3-Difluoro-5-nitroaniline (CAS 1803824-12-5)
- 4-(Difluoromethyl)pyrimidine-5-carboxylic acid (CAS 1340535-05-8)
- 4-(Difluoromethyl)-5-methoxy-2-(trifluoromethyl)nicotinic acid (CAS 1806036-52-1)
- 7-Bromo-6-methyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one (CAS 1456525-53-3)
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