8-chloro-6-methyl-1,2,3,4-tetrahydroquinoline CAS 176097-89-5
| CAS No. | 176097-89-5 |
| Molecular Formula | C10H12ClN |
| Molecular Weight | 181.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8-chloro-6-methyl-1,2,3,4-tetrahydroquinoline is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
8-chloro-6-methyl-1,2,3,4-tetrahydroquinoline (CAS 176097-89-5) is a high-purity analytical reference standard with the molecular formula C10H12ClN and a molecular weight of 181.66 g/mol.
8-chloro-6-methyl-1,2,3,4-tetrahydroquinoline (C10H12ClN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-chloro-6-methyl-1,2,3,4-tetrahydroquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12ClN |
| Molecular Weight | 181.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related chloro Standards
- 7-Chloro-8-methyl-1,2,3,4-tetrahydroquinoline (CAS 100642-29-3)
- (R)-7-Chloro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1055949-63-7)
- (R)-6-Chloro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1057246-77-1)
- 7-Chloro-8-methyl-1,2,3,4-tetrahydroisoquinoline (CAS 1066822-69-2)
- (6-Chloro-2,3-dihydro-1H-inden-1-yl)methanamine (CAS 1188141-98-1)
- (5-Chloro-2,3-dihydro-1H-inden-1-yl)methanamine (CAS 1188168-74-2)
- 6-Chloro-N-methyl-2,3-dihydro-1H-inden-1-amine (CAS 1188244-51-0)
- 3-(4-Chloro-phenyl)-pyrrolidine (CAS 120418-62-4)
Recommended Standards
- 8-chloro-5-methyl-1,2,3,4-tetrahydroquinoline (CAS 1698991-31-9)
- n-[(4-chlorophenyl)methyl]cyclopropanamine (CAS 19271-24-0)
- 8-Chloro-7-methyl-1,2,3,4-tetrahydroquinoline (CAS 1697759-53-7)
- ((1S,2S)-2-(3-Chlorophenyl)cyclopropyl)methanamine (CAS 1932780-32-9)
- N-(5-Chloro-2-methoxyphenyl)-2-(3-(furan-2-yl)-6-oxopyridazin-1(6H)-yl)acetamide (CAS 879055-07-9)
- 1-(2,6-Dichlorobenzyl)-1h-pyrazol-4-amine (CAS 512810-10-5)
- 2,4-Dichloro-1,5-difluoro-3-(trifluoromethoxy)benzene (CAS 1417566-99-4)
- Methyl 4-Morpholino-2-nitrobenzoate (CAS 404010-97-5)
- 1-(3-(Trifluoromethyl)pyridin-2-yl)pyrrolidine-3-carboxylic acid (CAS 1316222-63-5)
- 4-Cyclohexyl-5-(1-(dimethylamino)propyl)-4H-1,2,4-triazole-3-thiol (CAS 790232-41-6)
- (S)-C33 (CAS 2066488-39-7)
- (S)-2-aminopentan-1-ol hydrochloride (CAS 2025376-01-4)
- (S)-(5,6,7,8-Tetrahydroindolizin-8-yl)methanamine hydrochloride (CAS 1245646-28-9)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
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