Bisoprolol Impurity 14 CAS 177034-57-0
| CAS No. | 177034-57-0 |
| Molecular Formula | C12H18O3 |
| Molecular Weight | 210.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 210.27 g/mol gives Bisoprolol Impurity 14 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Bisoprolol Impurity 14 (CAS 177034-57-0) is a certified pharmaceutical impurity reference standard with the molecular formula C12H18O3 and a molecular weight of 210.27 g/mol.
Structurally, Bisoprolol Impurity 14 (C12H18O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 210.27 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Bisoprolol Impurity 14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H18O3 |
| Molecular Weight | 210.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
Related Bisoprolol Standards
- Bisoprolol Impurity 102 (CAS CATO-C4X-1247102)
- Bisoprolol Impurity 79 (CAS 1039828-27-7)
- Bisoprolol Impurity 82 (CAS 313975-07-4)
- Bisoprolol Impurity 51 (CAS 62911-12-0)
- Bisoprolol Impurity 52 (CAS 293302-44-0)
- Bisoprolol EP Impurity R (CAS 5790-46-5)
- Bisoprolol Impurity 101 (CAS CATO-C4X-1247101)
- Bisoprolol Impurity 83 (CAS CATO-C4X-124783)
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