Ambrisentan CAS 177036-94-1
| CAS No. | 177036-94-1 |
| Molecular Formula | C22H22N2O4 |
| Molecular Weight | 378.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ambrisentan (C22H22N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Ambrisentan (CAS 177036-94-1), molecular formula C22H22N2O4 and molecular weight 378.42 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ambrisentan under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H22N2O4 |
| Molecular Weight | 378.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Nitrogen Atoms | 2 |
Related Ambrisentan Standards
- rac Ambrisentan (CAS 713516-99-5)
- Ambrisentan Impurity 6 (CAS 1007358-76-0)
- rac Ambrisentan-d3 (CAS 1189479-60-4)
- Ambrisentan-D10 (CAS 1046116-27-1)
- Ambrisentan Methyl Ester (CAS 1106685-61-3)
- rac Ambrisentan Methyl Ester (CAS 1240470-84-1)
- Ambrisentan 4-Hydroxymethyl Analog Racemate (CAS 1106685-84-0)
- rac Ambrisentan-d3 Methyl Ester (CAS 1329837-75-3)
Recommended Standards
- Roxatidine Impurity 52 (CAS CATO-C4X-121352)
- Vonoprazan Impurity 257 (CAS CATO-C4X-1020257)
- Guaifenesin EP Impurity C (CAS 1797132-23-0)
- Aripiprazole Impurity 60 (CAS CATO-C4X-100860)
- Ethyl 8-(2-(morpholinomethyl)phenyl)-8-oxooctanoate (CAS 898751-61-6)
- N,N-dimethyl-1H-pyrazole-3-sulfonamide (CAS 925884-44-2)
- 1-(4-nitro-3-propoxyphenyl)piperidin-4-ol (CAS 1409764-52-8)
- 2,6-Dimethoxybenzenesulfonyl Chloride (CAS 145980-89-8)
- 1036760-17-4 (+/-)-tert-Butyl-8-oxo-7-azabicyclo[4.2.0]oct-3-ene-7-carboxylate MFCD20482006 (CAS 1036760-17-4)
- 2-(4-Methyl-6-(piperazin-1-yl)pyrimidin-2-yl)phenol (CAS 330982-03-1)
- N-(4-chlorophenyl)-1-((4-fluorophenyl)sulfonyl)pyrrolidine-2-carboxamide (CAS 317377-90-5)
- 5-Amino-1-(1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid ethyl ester (CAS 58113-07-8)
- 1-(1,3-Dimethyl-1H-pyrazol-4-yl)-2,2,2-trifluoroethanone (CAS 1174875-19-4)
- Insulin Degludec Impurity 19 (CAS CATO-C4X-215719)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com