5-Fluoro-2-(3,3-difluoroazetidin-1-yl)benzaldehyde CAS 1774893-74-1
| CAS No. | 1774893-74-1 |
| Molecular Formula | C10H8F3NO |
| Molecular Weight | 215.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-Fluoro-2-(3,3-difluoroazetidin-1-yl)benzaldehyde (CAS 1774893-74-1), a certified reference material (molecular formula C10H8F3NO, MW 215.17 g/mol) for analytical method development and quality control.
The molecular framework of 5-Fluoro-2-(3,3-difluoroazetidin-1-yl)benzaldehyde (C10H8F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 5-Fluoro-2-(3,3-difluoroazetidin-1-yl)benzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8F3NO |
| Molecular Weight | 215.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 6-Fluoro-2-(3,3-difluoroazetidin-1-yl)benzaldehyde 1779119-94-6 (CAS 1779119-94-6)
- 4-Fluoro-1-(2-methoxyethoxy)-2-nitrobenzene (CAS 1092496-30-4)
- 4-Fluoro-3-(2-hydroxypyrimidin-5-yl)benzonitrile (CAS 1111113-52-0)
- 2-(2-Fluoro-6-nitrophenyl)propane-1,3-diol (CAS 1131605-32-7)
- 1-Fluoro-2-(2-methoxyethoxy)-3-nitrobenzene (CAS 1233952-90-3)
- 2-Fluoro-3-(2-hydroxypyrimidin-5-yl)benzonitrile (CAS 1261965-61-0)
- 1-Fluoro-3-(2-methoxyethoxy)-2-nitrobenzene (CAS 131055-85-1)
- 1-fluoro-4-(2-methoxyethoxy)-2-nitrobenzene (CAS 1416626-24-8)
Recommended Standards
- 6-Methoxy-2-(trifluoromethyl)-1H-indole (CAS 174907-38-1)
- 2-(3,3-Difluoroazetidin-1-yl)-3-fluorobenzaldehyde (CAS 1779119-77-5)
- 5-Methoxy-2-(trifluoromethyl)-1H-indole (CAS 174734-34-0)
- (4R)-4-(3,4,5-Trifluorophenyl)pyrrolidin-2-one (CAS 1651179-16-6)
- 2-(tetrahydrofuran-2-yl)pyrrolidine (CAS 383127-91-1)
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