2-[(3-Bromophenyl)methyl]-4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidine-1,3-dione CAS 1775337-53-5
| CAS No. | 1775337-53-5 |
| Molecular Formula | C19H19BrN4O3 |
| Molecular Weight | 431.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-[(3-Bromophenyl)methyl]-4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidine-1,3-dione is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-[(3-Bromophenyl)methyl]-4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidine-1,3-dione (CAS 1775337-53-5), molecular formula C19H19BrN4O3 and molecular weight 431.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-[(3-Bromophenyl)methyl]-4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidine-1,3-dione (C19H19BrN4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-[(3-Bromophenyl)methyl]-4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidine-1,3-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H19BrN4O3 |
| Molecular Weight | 431.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Bromophenyl Standards
- 4-(5-(4-Bromophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)-4-oxobutanoic acid (CAS 309925-78-8)
- N-(4-Bromophenyl)-2-((4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl)thio)acetamide (CAS 1251704-20-7)
- 3-((6-(4-Bromophenyl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)propanoic acid (CAS 625376-46-7)
- 4-(4-bromophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-5,6-dihydrobenzo[h]quinazoline (CAS 956965-83-6)
- 1-((4-(4-Bromophenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-3,3-dimethylbutan-2-one (CAS 477329-71-8)
- 1-((4-(4-Bromophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-3,3-dimethylbutan-2-one (CAS 477330-45-3)
- 2-((2-(4-Bromophenyl)-2-oxoethyl)thio)-3-isobutylquinazolin-4(3H)-one (CAS 255865-18-0)
- 3-[(4-Bromophenyl)sulfanyl]-1-(3,5-dichlorophenyl)pyrrolidine-2,5-dione (CAS 301194-49-0)
Recommended Standards
- CITFP (CAS 155797-99-2)
- 2-((4-Bromo-N-(2-hydroxyethyl)phenyl)sulfonamido)-N-(4-fluorophenyl)acetamide (CAS 256521-73-0)
- Methyl 6-{bis[(tert-butoxy)carbonyl]amino}-5-bromopyridine-3-carboxylate (CAS 1393845-63-0)
- 3-(7-((4-Bromobenzyl)oxy)-4,8-dimethyl-2-oxo-2H-chromen-3-yl)propanoic acid (CAS 858751-27-6)
- 2-(5-Chloropyridin-3-yl)acetic acid (CAS 39891-11-7)
- (R)-1-(6-Fluoropyridin-3-yl)ethanamine hydrochloride (CAS 1956436-32-0)
- 5-Cyclopropyl-1-methyl-1H-1,2,3-triazol-4-amine (CAS 1369433-20-4)
- 3-methyl-1-[5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-5-amine (CAS 926234-78-8)
- 6-Bromo-4-methylpyridazin-3(2H)-one (CAS 1936342-70-9)
- 2-(4-(Difluoromethyl)-5-fluoro-3-(trifluoromethyl)pyridin-2-yl)acetic acid (CAS 1806021-47-5)
- tert-Butyl (S)-3-cyanomorpholine-4-carboxylate (CAS 1257856-86-2)
- MEthyl 5-(3-(trifluoromethyl)phenyl)picolinate (CAS 87789-82-0)
- 1,8-Naphthyridin-4-amine hydrochloride (CAS 1864015-59-7)
- Biotinyl-Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 1816258-36-2)
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