3-[(4-Bromophenyl)sulfanyl]-1-(3,5-dichlorophenyl)pyrrolidine-2,5-dione CAS 301194-49-0
| CAS No. | 301194-49-0 |
| Molecular Formula | C16H10BrCl2NO2S |
| Molecular Weight | 431.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-[(4-Bromophenyl)sulfanyl]-1-(3,5-dichlorophenyl)pyrrolidine-2,5-dione.
CATO supplies 3-[(4-Bromophenyl)sulfanyl]-1-(3,5-dichlorophenyl)pyrrolidine-2,5-dione (CAS 301194-49-0), a certified reference material (molecular formula C16H10BrCl2NO2S, MW 431.13 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, 3-[(4-Bromophenyl)sulfanyl]-1-(3,5-dichlorophenyl)pyrrolidine-2,5-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 431.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H10BrCl2NO2S |
| Molecular Weight | 431.13 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromophenyl Standards
- 4-(bis(4-Bromophenyl)amino)benzaldehyde (CAS 25069-38-9)
- 3-((6-(4-Bromophenyl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)propanoic acid (CAS 625376-46-7)
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Recommended Standards
- Dibutyltin Bis(Acetylacetonate) (CAS 22673-19-4)
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- 3-Fluoro-6-isopropoxy-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 2377612-06-9)
- N,5-Dimethylpyrimidin-4-amine (CAS 52698-53-0)
- 1-(5-Chlorobenzo[d]oxazol-2-yl)piperidin-3-amine hydrochloride (CAS 1431962-82-1)
- 3-Azepan-1-yl-2-methylpropanoic acid (CAS 31035-71-9)
- 1-tert-butyl 4-methyl azepane-1,4-dicarboxylate (CAS 1259065-07-0)
- 3-(3-(1-Isobutyl-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)-1,2,4-oxadiazol-5-yl)propanoic acid (CAS 1707727-45-4)
- Tributylethyltin (CAS 19411-60-0)
- 3-(3-Fluorophenyl)-1-benzhydryl azetidine (CAS 132924-41-5)
- 3,3,5-Trimethylazepane hydrochloride (CAS 86404-45-7)
- 8-Ethyl-4-(naphthalene-2-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326811-85-1)
- ([13C6]Leu14)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802078-39-2)
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