N-(3,4-Dichlorophenyl)-5-methyl-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide CAS 1775347-37-9
| CAS No. | 1775347-37-9 |
| Molecular Formula | C21H21Cl2N3O2 |
| Molecular Weight | 418.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(3,4-Dichlorophenyl)-5-methyl-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide (CAS 1775347-37-9) is a high-purity analytical reference standard with the molecular formula C21H21Cl2N3O2 and a molecular weight of 418.32 g/mol.
Structurally, N-(3,4-Dichlorophenyl)-5-methyl-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide (C21H21Cl2N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 418.32 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(3,4-Dichlorophenyl)-5-methyl-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H21Cl2N3O2 |
| Molecular Weight | 418.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 3-[3-(2,6-Dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]-1-[3-methyl-4-(propan-2-yl)phenyl]urea (CAS 329702-81-0)
- 543686-34-6 (3-(2,6-Dichlorophenyl)-5-methylisoxazol-4-yl)-N-(4-(diethylamino)phenyl)formamide MFCD01567353 (CAS 543686-34-6)
- (2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-N-[(thiophen-2-yl)methyl]prop-2-enamide (CAS 477888-80-5)
- 2-(2-{2-[(3,4-dichlorophenyl)amino]-1,3-thiazol-4-yl}ethyl)-2,3-dihydro-1H-isoindole-1,3-dione (CAS 861211-34-9)
- 2-{4-[5-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}-3-nitropyridine (CAS 1024018-46-9)
- (3-(2,6-Dichlorophenyl)-5-methylisoxazol-4-yl)(4-(pyrimidin-2-yl)piperazin-1-yl)methanone (CAS 546062-79-7)
- 3-{[(2,6-dichlorophenyl)methyl]sulfanyl}-5-[(E)-2-(phenylamino)ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338778-53-3)
- 4-[(2,3-Dichlorophenyl)sulfanyl]-6-(4-methylphenyl)-2-(methylsulfanyl)pyrimidine-5-carbonitrile (CAS 303985-08-2)
Recommended Standards
- 7-Fluoro-4-(4-fluorophenyl)-2-(4-(trifluoromethoxy)phenyl)phthalazin-1(2H)-one (CAS 161716-21-8)
- 3-[1-(3-Aminophenyl)-3-tert-Butyl-1H-pyrazol-5-yl]-1-(2,3-dichlorophenyl)urea (CAS 227622-98-2)
- Cis-3-((1H-imidazol-1-yl)methyl)-5-((4-chlorophenoxy)methyl)-3-(4-chlorophenyl)-2-methylisoxazolidine (CAS 114372-38-2)
- N-(4-Bromophenyl)-2-((4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 482640-17-5)
- Ethyl 1-(3-hydroxy-4-nitrophenyl)piperidine-4-carboxylate (CAS 927699-09-0)
- (7-Methylimidazo[1,2-a]pyrimidin-3-yl)methanamine (CAS 944900-31-6)
- N-(2-bromo-4-methylphenyl)benzamide (CAS 77791-07-2)
- Methyltetrazine-DBCO (CAS 1802238-48-7)
- 3-[4-[2-(2-aminoethoxy)ethylamino]-1-oxo-isoindolin-2-yl]piperidine-2,6-dione (CAS 2138439-15-1)
- 1-Chloro-2-(methylsulfinyl)benzene (CAS 7321-57-5)
- 2-Ethoxy-6-methylpyridine (CAS 18617-77-1)
- Tri-n-amylphosphineoxide (CAS 3084-47-7)
- N-(6-Bromopyridin-2-yl)-N-methylacetamide (CAS 1133116-43-4)
- Semaglutide impurity 59 (CAS CATO-C4X-222659)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com