2-{4-[5-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}-3-nitropyridine CAS 1024018-46-9
| CAS No. | 1024018-46-9 |
| Molecular Formula | C19H17Cl2N5O2 |
| Molecular Weight | 418.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-{4-[5-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}-3-nitropyridine.
2-{4-[5-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}-3-nitropyridine (CAS 1024018-46-9) is a high-purity analytical reference standard with the molecular formula C19H17Cl2N5O2 and a molecular weight of 418.28 g/mol.
Structurally, 2-{4-[5-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}-3-nitropyridine (C19H17Cl2N5O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 418.28 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H17Cl2N5O2 |
| Molecular Weight | 418.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related dichlorophenyl Standards
- (3-(2,6-Dichlorophenyl)-5-methylisoxazol-4-yl)(4-(pyrimidin-2-yl)piperazin-1-yl)methanone (CAS 546062-79-7)
- 2-(2-{2-[(3,4-dichlorophenyl)amino]-1,3-thiazol-4-yl}ethyl)-2,3-dihydro-1H-isoindole-1,3-dione (CAS 861211-34-9)
- N-(3,4-Dichlorophenyl)-5-methyl-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide (CAS 1775347-37-9)
- 3-[3-(2,6-Dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]-1-[3-methyl-4-(propan-2-yl)phenyl]urea (CAS 329702-81-0)
- 543686-34-6 (3-(2,6-Dichlorophenyl)-5-methylisoxazol-4-yl)-N-(4-(diethylamino)phenyl)formamide MFCD01567353 (CAS 543686-34-6)
- (2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-N-[(thiophen-2-yl)methyl]prop-2-enamide (CAS 477888-80-5)
- 1-[3-(2,6-Dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-5-(trifluoromethyl)-2,3-dihydro-1H-1,4-diazepine (CAS 439120-73-7)
- 3-{[(2,6-dichlorophenyl)methyl]sulfanyl}-5-[(E)-2-(phenylamino)ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338778-53-3)
Recommended Standards
- Maribavir Impurity 29 (CAS CATO-C4X-300729)
- 5-(Aminomethyl)-1-(4-chloro-2-(2-chlorobenzoyl)phenyl)-N,N-dimethyl-1H-1,2,4-triazole-3-carboxamide (CAS 102821-00-1)
- Resmetirom Impurity 47 (CAS CATO-C4X-291247)
- 4,4,5,5-Tetramethyl-2-(2-(3-(trifluoromethyl)benzyl)benzo[b]thiophen-7-yl)-1,3,2-dioxaborolane (CAS 1207970-76-0)
- (cyclopentyloxy)benzene (CAS 33186-68-4)
- 2-(2,4-Dichlorobenzyl)-5,6-dihydrobenzo[h]cinnolin-3(2H)-one (CAS 478042-22-7)
- 6-(2,4-Difluorophenyl)pyrimidine-4-carboxylic acid (CAS 1207723-93-0)
- Piracetam Impurity 21 (CAS CATO-C4X-123521)
- DL-Cloprostenol Sodium Salt (CAS 55028-72-3)
- (3E)-1,1,1-Trifluoro-4-{[(4-fluorophenyl)methoxy]amino}pent-3-en-2-one (CAS 303986-96-1)
- 4-Chloro-1-((2-fluorophenoxy)methyl)-1,2-dihydro-3h-pyrazol-3-imine (CAS 1006435-98-8)
- VApreotide (acetate) (CAS 849479-74-9)
- Calcium 5-methyltetrahydrofolate (CAS 26560-38-3)
- Semaglutide Impurity 1(OtBu-Ste-D-γGlu(OtBu)-AEEA-AEEA-OH) (CAS CATO-C4X-22261)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com