1-(4-Chlorobenzoyl)-4-{[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]methyl}piperidine CAS 1775403-33-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1775403-33-2
Molecular FormulaC18H22ClN3O2
Molecular Weight347.84 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(4-Chlorobenzoyl)-4-{[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]methyl}piperidine CAS 1775403-33-2 chemical structure

Description

1-(4-Chlorobenzoyl)-4-{[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]methyl}piperidine (CAS 1775403-33-2) is a high-purity analytical reference standard with the molecular formula C18H22ClN3O2 and a molecular weight of 347.84 g/mol.

The molecular framework of 1-(4-Chlorobenzoyl)-4-{[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]methyl}piperidine (C18H22ClN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H22ClN3O2
Molecular Weight347.84 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1994
Halogen ContentCl-containing
Nitrogen Atoms3

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