2-(2-Chlorophenyl)-1-(4-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidin-1-yl)ethan-1-one CAS 1775495-20-9
| CAS No. | 1775495-20-9 |
| Molecular Formula | C22H21ClFN3O2 |
| Molecular Weight | 413.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-Chlorophenyl)-1-(4-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidin-1-yl)ethan-1-one.
2-(2-Chlorophenyl)-1-(4-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidin-1-yl)ethan-1-one (CAS 1775495-20-9) is a high-purity analytical reference standard with the molecular formula C22H21ClFN3O2 and a molecular weight of 413.87 g/mol.
The molecular framework of 2-(2-Chlorophenyl)-1-(4-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidin-1-yl)ethan-1-one (C22H21ClFN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H21ClFN3O2 |
| Molecular Weight | 413.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- {4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}methyl 3-methylbenzoate (CAS 320424-12-2)
- 4-(4-Chlorophenyl)-1-[(4-fluorophenyl)methyl]-2-[(E)-(phenylmethylidene)amino]-1H-pyrrole-3-carbonitrile (CAS 250713-91-8)
- N-(2-(2-(2-(4-Chlorophenyl)acetyl)hydrazine-1-carbonyl)phenyl)thiophene-2-carboxamide (CAS 1090837-09-4)
- N-(5-(3-(2-Chlorophenyl)acryloyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)furan-2-carboxamide (CAS 1351663-94-9)
- 3-(2-Chlorophenyl)-N-(6-ethoxybenzo[d]thiazol-2-yl)-5-methylisoxazole-4-carboxamide (CAS 545430-77-1)
- Ethyl 1-(5-(3-(2-chlorophenyl)ureido)pyridin-2-yl)-3,5-dimethyl-1H-pyrazole-4-carboxylate (CAS 477712-85-9)
- Methyl 4-(4-chlorophenyl)-1-(3,4-dimethoxyphenethyl)-2-methyl-1H-pyrrole-3-carboxylate (CAS 881041-57-2)
- (E)-[(4-Chlorophenyl)methoxy]({1-[3-(morpholin-4-yl)-5-(trifluoromethyl)pyridin-2-yl]ethylidene})amine (CAS 866145-14-4)
Recommended Standards
- 3,5-Dibromo-1-[(4-bromo-2-fluorophenyl)methyl]-1H-1,2,4-triazole (CAS 1240565-05-2)
- Tofacitinib Impurity 8 (CAS CATO-C4X-10798)
- {4-[(4-methylphenyl)sulfanyl]-3-nitrophenyl}methyl 4-chlorobenzoate (CAS 303988-37-6)
- 3-(Bis(4-methoxybenzyl)amino)-5-chloro-2-fluorobenzaldehyde (CAS 2812579-97-6)
- tert-butyl 4-methyl-3,6-dihydrooxazine-2-carboxylate (CAS 225656-51-9)
- (1S,4s)-1,4-bis(4-bromophenyl)-1,4-bis(methoxymethoxy)cyclohexane (CAS 2177264-24-1)
- N-(4-(Chloromethyl)benzyl)acetamide (CAS 223512-41-2)
- 3-Morpholino-1-phenylpyrrolidine-2,5-dione (CAS 53541-45-0)
- (S)-5-(1-Amino-3-hydroxypropan-2-yl)-2-methoxyphenol (CAS 1212797-76-6)
- 4-Amino-3-bromo-5-(difluoromethyl)pyridine-2-sulfonyl chloride (CAS 1806838-26-5)
- 4'-Methyl-[1,1'-biphenyl]-3-amine hydrochloride (CAS 1049728-25-7)
- 1-(3-Ethoxyphenyl)propan-1-one (CAS 1183722-02-2)
- N-(1-Ethyl-2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)pentanamide (CAS 392236-66-7)
- Peptide WE-14 (CAS 115136-18-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com