Ethyl 1-(5-(3-(2-chlorophenyl)ureido)pyridin-2-yl)-3,5-dimethyl-1H-pyrazole-4-carboxylate CAS 477712-85-9
| CAS No. | 477712-85-9 |
| Molecular Formula | C20H20ClN5O3 |
| Molecular Weight | 413.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ethyl 1-(5-(3-(2-chlorophenyl)ureido)pyridin-2-yl)-3,5-dimethyl-1H-pyrazole-4-carboxylate (C20H20ClN5O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Ethyl 1-(5-(3-(2-chlorophenyl)ureido)pyridin-2-yl)-3,5-dimethyl-1H-pyrazole-4-carboxylate (CAS 477712-85-9), a certified reference material (molecular formula C20H20ClN5O3, MW 413.86 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 1-(5-(3-(2-chlorophenyl)ureido)pyridin-2-yl)-3,5-dimethyl-1H-pyrazole-4-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H20ClN5O3 |
| Molecular Weight | 413.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Ethyl Standards
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- N-(2-(2-(2-(4-Chlorophenyl)acetyl)hydrazine-1-carbonyl)phenyl)thiophene-2-carboxamide (CAS 1090837-09-4)
- N-(5-(3-(2-Chlorophenyl)acryloyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)furan-2-carboxamide (CAS 1351663-94-9)
- 3-(2-Chlorophenyl)-N-(6-ethoxybenzo[d]thiazol-2-yl)-5-methylisoxazole-4-carboxamide (CAS 545430-77-1)
- Methyl 4-(4-chlorophenyl)-1-(3,4-dimethoxyphenethyl)-2-methyl-1H-pyrrole-3-carboxylate (CAS 881041-57-2)
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Recommended Standards
- (E)-5-(4-(1H-1,2,4-triazol-1-yl)benzylidene)-2-((2-chloro-6-fluorobenzyl)thio)-3,5-dihydro-4H-imidazol-4-one (CAS 860648-84-6)
- Tofacitinib Impurity 8 (CAS CATO-C4X-10798)
- Finerenone Impurity 286 (CAS CATO-C4X-2880286)
- 3,5-Dibromo-1-[(4-bromo-2-fluorophenyl)methyl]-1H-1,2,4-triazole (CAS 1240565-05-2)
- 4-((Cyclohexyloxy)methyl)-3-fluorobenzaldehyde (CAS 1443305-87-0)
- CAS 2260670-05-9 (CAS 2260670-05-9)
- Ethyl 4-chloropyrido[2,3-d]pyrimidine-2-carboxylate (CAS 1286330-18-4)
- 3-Bromo-5-nitropyrazole (CAS 1208314-00-4)
- 4-Oxo-4-pyrrolidin-1-ylbutanoic acid (CAS 69338-35-8)
- 2-[(E)-[(4-Chlorophenyl)methylidene]amino]-1-[(2,4-dichlorophenyl)methyl]-4-phenyl-1H-pyrrole-3-carbonitrile (CAS 303150-00-7)
- Ethyl 3-(1-methyl-1h-pyrazol-4-yl)isoxazole-5-carboxylate (CAS 1356543-58-2)
- 5-Chloro-7-methylbenzofuran (CAS 90895-03-7)
- methyl 5-methylpyrimidine-4-carboxylate (CAS 1803804-13-8)
- DAPK Substrate Peptide (CAS 386769-53-5)
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