4-[(4-Fluorophenyl)methyl]-3-[1-(thiophene-3-carbonyl)piperidin-4-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one CAS 1775524-36-1
| CAS No. | 1775524-36-1 |
| Molecular Formula | C19H19FN4O2S |
| Molecular Weight | 386.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-[(4-Fluorophenyl)methyl]-3-[1-(thiophene-3-carbonyl)piperidin-4-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775524-36-1), molecular formula C19H19FN4O2S and molecular weight 386.44 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-[(4-Fluorophenyl)methyl]-3-[1-(thiophene-3-carbonyl)piperidin-4-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one (C19H19FN4O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 4-[(4-Fluorophenyl)methyl]-3-[1-(thiophene-3-carbonyl)piperidin-4-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H19FN4O2S |
| Molecular Weight | 386.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- N-(2-Fluorophenyl)-2-(4-(5-(furan-2-yl)-1,3,4-thiadiazol-2-yl)piperidin-1-yl)acetamide (CAS 1226456-53-6)
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Recommended Standards
- (3'R,4'S,5'S,6'R)-6-(4-Ethylbenzyl)-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[isobenzofuran-1,2'-pyran]-3',4',5'-triol (CAS 1704743-06-5)
- 4-((17-Hydroxy-3,6,9,12,15-pentaoxaheptadecyl)oxy)benzaldehyde (CAS 191984-39-1)
- (4AR,6R,7R,8S,8aR)-7,8-Bis(benzyloxy)-2-methyl-hexahydropyrano[3,2-d][1,3]dioxin-6-ol (CAS 170078-65-6)
- Methyl 3-[(2-cyano-3-methylphenyl)sulfamoyl]-1-benzothiophene-2-carboxylate (CAS 1955506-63-4)
- 1-[4-(tert-Butyl)phenyl]cyclopentanecarboxylic Acid (CAS 923249-62-1)
- 4-Nitrophenyl acrylate, 97% (CAS 2123-85-5)
- (S)-4-(tert-Butoxy)-2-cyclobutyl-4-oxobutanoic acid (CAS 1923056-94-3)
- 2-Isopropyl-5-(pyrrolidin-3-yl)-1,3,4-oxadiazole (CAS 1004620-18-1)
- 5-Bromo-7-fluoroquinoxaline (CAS 1628908-19-9)
- 2-(Difluoromethyl)-3-iodopyridine-5-carboxylic acid (CAS 1487221-01-1)
- Methyl 5-(cyanomethyl)-2-hydroxybenzoate (CAS 4900-25-8)
- 3-(Hydroxymethyl)-3-methylpyrrolidin-2-one (CAS 1781900-40-0)
- 1-Stearoyl-sn-glycerol (CAS 22610-61-3)
- (Cys2)-Neuropeptide Y-8-aminooctanoyl-(D-Cys27)-Neuropeptide Y (25-32) (H-3298.0500) (CAS 128806-04-2)
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