2-((4-Fluorophenyl)sulfonyl)-1-(4-methoxyphenyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine CAS 899949-24-7
| CAS No. | 899949-24-7 |
| Molecular Formula | C20H19FN2O3S |
| Molecular Weight | 386.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-((4-Fluorophenyl)sulfonyl)-1-(4-methoxyphenyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine (CAS 899949-24-7) is a high-purity analytical reference standard with the molecular formula C20H19FN2O3S and a molecular weight of 386.44 g/mol.
The molecular framework of 2-((4-Fluorophenyl)sulfonyl)-1-(4-methoxyphenyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine (C20H19FN2O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H19FN2O3S |
| Molecular Weight | 386.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- N-(2-Fluorophenyl)-2-(4-(5-(furan-2-yl)-1,3,4-thiadiazol-2-yl)piperidin-1-yl)acetamide (CAS 1226456-53-6)
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- 4-[(4-Fluorophenyl)methyl]-3-[1-(thiophene-3-carbonyl)piperidin-4-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775524-36-1)
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Recommended Standards
- 2-((4-Ethyl-5-(2-hydroxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(5-fluoro-2-methylphenyl)acetamide (CAS 835896-49-6)
- 2-(Benzylthio)-4-(2,4-difluorophenoxy)thieno[3,2-d]pyrimidine (CAS 478067-48-0)
- 2-((3,4-Dimethoxyphenyl)amino)-1-(1h-indol-3-yl)-2-phenylethan-1-one (CAS 924712-67-4)
- 2,3-Bis(3,4-Dimethoxybenzyl)butyrolactone (CAS 25488-59-9)
- (5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)isoxazol-3-yl)methyl 2-oxo-2H-pyran-5-carboxylate (CAS 1203387-76-1)
- 3,4-Dichloro-5-(difluoromethoxy)phenylacetonitrile (CAS 1807052-41-0)
- 2-((1-(3-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide (CAS 851078-95-0)
- 2-Methylcyclopentan-1-amine (CAS 41223-14-7)
- 1-Methyl-3-nitro-1H-pyrazole-4-carboxamide (CAS 39205-70-4)
- 3-Butyl-2-ethoxy-6-hydroxypyrimidin-4(3H)-one (CAS 205440-30-8)
- N-(4-(Aminomethyl)-5-cyclopropoxypyridin-3-yl)methanesulfonamide (CAS 1243444-39-4)
- 1,5-Pentanediol Bis(methanesulfonate) (CAS 2374-22-3)
- 5-chloro-1-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid (CAS 1780746-87-3)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
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