3-[1-(3-Fluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one CAS 1775526-12-9
| CAS No. | 1775526-12-9 |
| Molecular Formula | C22H23FN4O3 |
| Molecular Weight | 410.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-[1-(3-Fluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775526-12-9) is a high-purity analytical reference standard with the molecular formula C22H23FN4O3 and a molecular weight of 410.44 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3-[1-(3-Fluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 410.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 3-[1-(3-Fluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H23FN4O3 |
| Molecular Weight | 410.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fluorobenzoyl Standards
- 3-[1-(4-Fluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775337-52-4)
- 3-[1-(2-Fluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775507-37-3)
- 3-(2-(4-(4-Fluorobenzoyl)piperidin-1-yl)ethyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one (CAS 76330-71-7)
- N-(2-{4-[1-(4-fluorobenzoyl)-1H-pyrazol-3-yl]phenoxy}ethyl)-N-methylpyridin-2-amine (CAS 955976-52-0)
- 2-(4-Fluorobenzoyl)-6-(pyridin-3-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-3-amine (CAS 625377-67-5)
- 2-(4-Fluorobenzoyl)-4-(pyridin-3-yl)-5H,6H,7H,8H-thieno[2,3-b]quinolin-3-amine (CAS 340818-05-5)
- 1-(4-Fluorobenzoyl)-3,4-bis(4-methoxyphenyl)-1H-pyrazole (CAS 955975-67-4)
- 6-(2-(4-(4-Fluorobenzoyl)piperidin-1-yl)ethyl)-7-methyl-2H-thiazolo[3,2-a]pyrimidin-5(3H)-one (CAS 86487-64-1)
Recommended Standards
- 4-[(4-Fluorophenyl)methyl]-3-[1-(2-phenoxyacetyl)piperidin-4-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775541-85-9)
- 4-[(4-Fluorophenyl)methyl]-3-[1-(3-methoxybenzoyl)piperidin-4-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775379-13-9)
- Tris(2,5-dimethylphenyl) phosphate (CAS 19074-59-0)
- 1-(3-Methoxyphenyl)-2-(triphenylphosphoranylidene)ethanone (CAS 56937-78-1)
- 4,6-Dichloro-5-methyl-2-phenylpyrimidine (CAS 33655-33-3)
- 3-Bromobenzaldehyde Diethyl Acetal (CAS 75148-49-1)
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- 2-((2,6-Di(pyrrolidin-1-yl)pyrimidin-4-yl)amino)ethanol (CAS 157014-18-1)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com