3-[1-(2H-1,3-Benzodioxole-5-carbonyl)piperidin-4-yl]-4-[(4-methylphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one CAS 1775558-61-6
| CAS No. | 1775558-61-6 |
| Molecular Formula | C23H24N4O4 |
| Molecular Weight | 420.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-[1-(2H-1,3-Benzodioxole-5-carbonyl)piperidin-4-yl]-4-[(4-methylphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one.
3-[1-(2H-1,3-Benzodioxole-5-carbonyl)piperidin-4-yl]-4-[(4-methylphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775558-61-6) is a high-purity analytical reference standard with the molecular formula C23H24N4O4 and a molecular weight of 420.46 g/mol.
The molecular framework of 3-[1-(2H-1,3-Benzodioxole-5-carbonyl)piperidin-4-yl]-4-[(4-methylphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (C23H24N4O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-[1-(2H-1,3-Benzodioxole-5-carbonyl)piperidin-4-yl]-4-[(4-methylphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H24N4O4 |
| Molecular Weight | 420.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 4 |
Related H Standards
- 1-(2H-1,3-Benzodioxole-5-carbonyl)-4-{[3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidine (CAS 1775399-14-8)
- 2-(2H-1,3-Benzodioxole-5-carbonyl)-6-(furan-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-3-amine (CAS 674807-15-9)
- 3-[1-(2H-1,3-Benzodioxole-5-carbonyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775380-33-0)
- 3-(1,3-Benzodioxole-5-Carbonyl)-5-Fluoro-1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyrimidine-2,4-Dione (CAS 74234-11-0)
- 1-(2H-1,3-Benzodioxole-5-carbonyl)-4-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]piperidine (CAS 352033-96-6)
- 2-(2H-1,3-Benzodioxole-5-carbonyl)-6-methyl-4-(thiophen-2-yl)-5H,6H,7H,8H-thieno[2,3-b]1,6-naphthyridin-3-amine (CAS 354555-88-7)
- 2-(2H-1,3-Benzodioxole-5-carbonyl)-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinolin-3-amine (CAS 625370-69-6)
- 1,3-Benzodioxole-N-phthalimido DL-threo-Droxidopa-13C2,15N (CAS 1330188-86-7)
Recommended Standards
- 172927-65-0 Sibrafiban [USAN:INN:BAN] ((1-(2-((4-(amino(hydroxyimino)methyl)benzoyl)amino)-1-oxopropyl)-4-piperidinyl)oxy)acetic acid ethyl ester Ro 48-3657 Sibrafiban Acetic acid, ((1-(2-((4-(amino(hydroxyimino)methyl)benzoyl)amino)-1-oxopropyl)-4-piperidinyl)oxy)-, ethyl ester, (S-(Z))- Ethyl (Z)-((1-(N-((p-hydroxyamidino)benzoyl)-L-alanyl)-4-piperidyl)oxy)acetate RO 48-3657/001 (CAS 172927-65-0)
- Brensocatib (CAS 1802148-05-5)
- (S)-Ethyl 2-((1-(2-(4-(N-hydroxycarbamimidoyl)benzamido)propanoyl)piperidin-4-yl)oxy)acetate (CAS 170094-62-9)
- 6-Amino-4-(4-methoxyphenyl)-1,3-diphenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (CAS 188199-07-7)
- tert-Butyl 5-amino-1,3-dihydrospiro[indene-2,3'-pyrrolidine]-1'-carboxylate (CAS 1934888-66-0)
- 5-Hydroxy-2-(hydroxymethyl)pyridin-4(1H)-one (CAS 31883-16-6)
- Ethyl 1-methylpiperazine-2-carboxylate (CAS 476493-07-9)
- (e)-3-(4-Methoxy-3-((o-tolyloxy)methyl)phenyl)acrylic acid (CAS 512809-89-1)
- (2E)-1-[1-(Benzenesulfonyl)-1H-pyrrol-3-yl]-3-(dimethylamino)prop-2-en-1-one (CAS 478064-06-1)
- N-(Benzo[d]thiazol-2-yl)-1H-imidazole-4-sulfonamide (CAS 1491415-96-3)
- 8-Chlorotetrazolo[1,5-a]pyridine (CAS 40971-88-8)
- (4-(1,3-Dioxolan-2-yl)phenyl)(cyclopentyl)methanone (CAS 898760-88-8)
- 6-Isopropoxy-9-oxo-9H-xanthene-2-carboxylic acid (CAS 33458-93-4)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
Why CATO?
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