3-[1-(3,5-Dimethoxybenzoyl)piperidin-4-yl]-4-[(4-fluorophenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one CAS 1775559-36-8
| CAS No. | 1775559-36-8 |
| Molecular Formula | C23H25FN4O4 |
| Molecular Weight | 440.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 440.47 g/mol gives 3-[1-(3,5-Dimethoxybenzoyl)piperidin-4-yl]-4-[(4-fluorophenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-[1-(3,5-Dimethoxybenzoyl)piperidin-4-yl]-4-[(4-fluorophenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775559-36-8), a certified reference material (molecular formula C23H25FN4O4, MW 440.47 g/mol) for analytical method development and quality control.
Structurally, 3-[1-(3,5-Dimethoxybenzoyl)piperidin-4-yl]-4-[(4-fluorophenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (C23H25FN4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 440.47 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-[1-(3,5-Dimethoxybenzoyl)piperidin-4-yl]-4-[(4-fluorophenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H25FN4O4 |
| Molecular Weight | 440.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Dimethoxybenzoyl Standards
- 1-(3,5-Dimethoxybenzoyl)-4-{[3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidine (CAS 1775467-68-9)
- 2-(3,4-Dimethoxybenzoyl)-6-(furan-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-3-amine (CAS 625377-62-0)
- (+)-5-(1-(3,4-Dimethoxybenzoyl)-1,2,3,4-tetrahydroquinolin-6-yl)-6-methyl-3,6-dihydro-2H-1,3,4-thiadiazin-2-one (CAS 147527-31-9)
- 4-(3,4-Dimethoxybenzoyl)-1-(2-(dimethylamino)ethyl)-3-hydroxy-5-(4-nitrophenyl)-1H-pyrrol-2(5H)-one (CAS 618080-83-4)
- 1-(2,4-Dimethoxybenzoyl)-4-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidine (CAS 1775455-42-9)
- 3-[1-(3,5-Dimethoxybenzoyl)piperidin-4-yl]-4-(4-methylphenyl)-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775432-23-9)
- 1-(3,4-Dimethoxybenzoyl)-4-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]piperidine (CAS 1775309-81-3)
- 1-(2,4-Dimethoxybenzoyl)-4-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]piperidine (CAS 1775399-42-2)
Recommended Standards
- Lesinurad Impurity 31 (CAS 1533519-99-1)
- 3-[1-(3-Fluoro-4-methoxybenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775559-75-5)
- 2-((5-Carbamoyl-1-methyl-1H-pyrrole)-3-sulfonamido)-5-(indolin-1-yl)benzoic acid (CAS 1445573-99-8)
- 2-((4-(N-(4-ethoxyphenyl)sulfamoyl)phenyl)carbamoyl)benzoic acid (CAS 433315-09-4)
- 5-Methoxy-[1,2,4]triazolo[1,5-a]pyrazine (CAS 1823902-98-2)
- 7-phenyl-2,3-dihydro-1H-indol-2-one (CAS 31676-48-9)
- n-(2,5-Dimethylbenzyl)-2-methylpropan-1-amine (CAS 1043799-04-7)
- Direct Yellow 26 (CAS 2829-42-7)
- 2-((3-Methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040631-85-3)
- 5-Fluoro-1H-indole-6-carbonitrile (CAS 1201149-04-3)
- Calcitonin Impurity 4 (CAS CATO-C4X-22184)
- 1-(Azidoacetyl)-3,5-dimethylpiperidine (CAS 1248154-95-1)
- 3-(1,1-Difluoroethyl)benzoic acid (CAS 55805-17-9)
- Palmitoyl Tetrapeptide-7 (CAS 221227-05-0)
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