3-[1-(3-Fluoro-4-methoxybenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one CAS 1775559-75-5
| CAS No. | 1775559-75-5 |
| Molecular Formula | C23H25FN4O4 |
| Molecular Weight | 440.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 440.47 g/mol gives 3-[1-(3-Fluoro-4-methoxybenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-[1-(3-Fluoro-4-methoxybenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775559-75-5), a certified reference material (molecular formula C23H25FN4O4, MW 440.47 g/mol) for analytical method development and quality control.
The molecular framework of 3-[1-(3-Fluoro-4-methoxybenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (C23H25FN4O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H25FN4O4 |
| Molecular Weight | 440.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fluoro Standards
- 3-(1-((2-Fluoro-[1,1'-biphenyl]-4-yl)oxy)ethyl)-1-((4-fluorophenyl)sulfonyl)-1H-pyrazole (CAS 477711-02-7)
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- 3-Fluoro-4-((6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yl)oxy)aniline (CAS 960299-67-6)
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- 5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-N-(2-hydroxy-3-morpholinopropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide (CAS 627908-92-3)
- 5-[((3Z)-5-Fluoro-2-oxo-1,2-dihydroindol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid [2-hydroxy-3-(morpholin-4-yl)propyl]amide (CAS 452104-85-7)
Recommended Standards
- 3-[1-(3,5-Dimethoxybenzoyl)piperidin-4-yl]-4-[(4-fluorophenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775559-36-8)
- 2-((4-(N-(4-ethoxyphenyl)sulfamoyl)phenyl)carbamoyl)benzoic acid (CAS 433315-09-4)
- Lesinurad Impurity 31 (CAS 1533519-99-1)
- 5-(4-Hydroxy-3-methoxybenzylidene)-2-(4-(4-nitrophenyl)piperazin-1-yl)thiazol-4(5H)-one (CAS 844447-18-3)
- n-(2-(Isopropylamino)ethyl)cyclopropanecarboxamide (CAS 1249940-27-9)
- 4-Bromo-2-aminobenzoic acid methyl ester (CAS 135484-83-2)
- 2-{pyrrolo[2,1-f][1,2,4]triazin-5-yl}ethan-1-amine (CAS 1368182-05-1)
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