3-[1-(2,6-Difluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one CAS 1775561-05-1
| CAS No. | 1775561-05-1 |
| Molecular Formula | C22H22F2N4O3 |
| Molecular Weight | 428.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 3-[1-(2,6-Difluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (C22H22F2N4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 428.43 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-[1-(2,6-Difluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775561-05-1) is a high-purity analytical reference standard with the molecular formula C22H22F2N4O3 and a molecular weight of 428.43 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-[1-(2,6-Difluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H22F2N4O3 |
| Molecular Weight | 428.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Difluorobenzoyl Standards
- 3-[1-(3,4-Difluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775444-57-9)
- 3-[1-(2,5-Difluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775544-13-2)
- 4-[(3,4-Difluorobenzoyl)Amino]-5-(3-Methoxypropyl-Pentylamino)-5-Oxopentanoic Acid (CAS 111106-23-1)
- 4-(2,6-Difluorobenzoyl)-1-(3-methoxybenzyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 317833-52-6)
- 4-(2,6-Difluorobenzoyl)-1-[(4-methoxyphenyl)methyl]-3-methyl-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 317833-54-8)
- 4-(2,6-Difluorobenzoyl)-3-methyl-1-(4-nitrobenzyl)-3,4-dihydroquinoxalin-2(1H)-one (CAS 317833-45-7)
- 3-{[4-(2,6-difluorobenzoyl)-3-methyl-2-oxo-1,2,3,4-tetrahydroquinoxalin-1-yl]methyl}benzonitrile (CAS 317833-44-6)
- 8-Benzyl-4-(2,4-difluorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326811-14-6)
Recommended Standards
- (2S,3R,4S,5S,6R)-2-(4-Allylphenoxy)-6-((((2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)methyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 499-33-2)
- 3-[1-(3-Fluoro-4-methoxybenzoyl)piperidin-4-yl]-4-[(4-fluorophenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775506-76-7)
- (E)-N'-(4-(Phenylethynyl)benzylidene)-2-(trifluoromethyl)benzenesulfonohydrazide (CAS 2477727-79-8)
- 1,2-Cyclohexylidene Tetra-O-acetyl myo-Inositol (CAS 39110-61-7)
- 1-(4-Nitrophenyl)-1H-indole (CAS 25688-27-1)
- 2-(3,4-Dichlorophenyl)-N-methylacetamide (CAS 16505-75-2)
- 3-(Isopropylthio)-1,2,4-triazin-5-amine (CAS 187099-36-1)
- 2-Fluoro-9H-carbazole (CAS 391-53-7)
- n-Methyl-1-(2-nitrophenyl)methanesulfonamide (CAS 106840-38-4)
- Epinephrine Impurity 44 (CAS 2947-00-4)
- 2-Allyloxyphenol (CAS 1126-20-1)
- 3-Chloro-N-(7-methyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]oxazepin-2-yl)propanamide (CAS 866152-00-3)
- 1-(2-Phenylbenzofuran-5-yl)ethanone (CAS 121045-41-8)
- Endo-Ala35-Tirzepatide (CAS CATO-CPTD788687)
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