4-Bromo-1-fluoro-2-(4-methylbenzyl)benzene CAS 1776111-97-7
| CAS No. | 1776111-97-7 |
| Molecular Formula | C14H12BrF |
| Molecular Weight | 279.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Bromo-1-fluoro-2-(4-methylbenzyl)benzene (C14H12BrF) is characterized by fluorine/bromine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-Bromo-1-fluoro-2-(4-methylbenzyl)benzene (CAS 1776111-97-7), molecular formula C14H12BrF and molecular weight 279.15 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H12BrF |
| Molecular Weight | 279.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
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Recommended Standards
- 5-Bromo-4-isobutoxythiophene-2-carboxylic acid (CAS 1707609-61-7)
- 2-(3-Bromo-5-methyl-benzenesulfonyl)-ethanol (CAS 1823247-06-8)
- 1-Bromo-4-(ethylsulfonyl)-2-methoxybenzene (CAS 1614246-34-2)
- 2-(3-Bromo-2-methyl-benzenesulfonyl)-ethanol (CAS 1823315-63-4)
- Ethyl 6-formyl-5-(1H-indol-4-yl)nicotinate (CAS 653573-29-6)
- Methyl 5-Methoxy-2-methylbenzoxazole-7-carboxylate (CAS 1221792-76-2)
- 4-Methoxy-1-benzofuran-7-carbonitrile (CAS 1258959-97-5)
- 2-(2-Nitrophenyl)acetaldehyde (CAS 1969-73-9)
- 2-(Benzo[4,5]thiazolo[2,3-c][1,2,4]triazol-3-ylthio)-N-(4-sulfamoylphenyl)acetamide (CAS 303788-24-1)
- 5-Bromo-3-chloro-7-azaindole (CAS 951626-91-8)
- Fmoc-L-α-allylproline (CAS 1631046-97-3)
- Methyl 1-((tert-butoxycarbonyl)amino)-2-vinylcyclopropanecarboxylate (CAS 1201943-62-5)
- Bevantolol Impurity 30 (CAS CATO-C4X-241130)
- Tirzepatide Impurity 15 (CAS CATO-C4X-324015)
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