4-chloro-2,3,6-trifluoroaniline CAS 177785-44-3
| CAS No. | 177785-44-3 |
| Molecular Formula | C6H3ClF3N |
| Molecular Weight | 181.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 181.54 g/mol gives 4-chloro-2,3,6-trifluoroaniline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-chloro-2,3,6-trifluoroaniline (CAS 177785-44-3), a certified reference material (molecular formula C6H3ClF3N, MW 181.54 g/mol) for analytical method development and quality control.
The molecular framework of 4-chloro-2,3,6-trifluoroaniline (C6H3ClF3N) is characterized by a nitrile group, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-chloro-2,3,6-trifluoroaniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H3ClF3N |
| Molecular Weight | 181.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related chloro Standards
- 5-Chloro-3-(difluoromethyl)-2-fluoropyridine (CAS 1119718-20-5)
- 2-Chloro-4-(difluoromethyl)-3-fluoropyridine (CAS 1262413-59-1)
- 4-Chloro-2-(trifluoromethyl)pyridine (CAS 131748-14-6)
- 3-Chloro-5-(difluoromethyl)-2-fluoro-pyridine (CAS 1374659-45-6)
- 4-Chloro-3-(difluoromethyl)-2-fluoropyridine (CAS 1804703-92-1)
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Recommended Standards
- Copperaluminumoxide (CAS 12042-92-1)
- 4-Chloro-3-(difluoromethyl)-5-fluoropyridine (CAS 1804950-73-9)
- 1-Bromo-3-chlorobicyclo[1.1.1]Pentane (CAS 155635-19-1)
- 2-Chloro-4-(difluoromethyl)-6-fluoropyridine (CAS 1805202-82-7)
- 7-(Trifluoromethoxy)-3,4-dihydroquinolin-2(1H)-one (CAS 1803606-58-7)
- 3-Chloro-α-methyl-4-pyridinemethanol (CAS 886856-92-4)
- 5,5'-(Propane-2,2-diyl)bis(2-(2-(furan-2-yl)propan-2-yl)furan) (CAS 61093-48-9)
- 3-(4-Chlorophenyl)-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1030421-13-6)
- Ethyl 1-(4,6-dimethylpyrimidin-2-yl)-1H-1,2,3-triazole-4-carboxylate (CAS 860784-44-7)
- 2-Nitro-5-(pyrrolidin-1-yl)aniline (CAS 289913-98-0)
- Glimepiride Impurity 14 (CAS 38258-74-1)
- N-{4-[N-hydroxyethanimidoyl]phenyl}cyclopropanecarboxamide (CAS 1000932-84-2)
- Landiolol Impurity 84 HCl (CAS CATO-C4X-262184)
- Semaglutide impurity 48 (CAS CATO-C4X-222648)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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