4-Chloro-3-(difluoromethyl)-5-fluoropyridine CAS 1804950-73-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1804950-73-9
Molecular FormulaC6H3ClF3N
Molecular Weight181.54 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Chloro-3-(difluoromethyl)-5-fluoropyridine CAS 1804950-73-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 181.54 g/mol gives 4-Chloro-3-(difluoromethyl)-5-fluoropyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 4-Chloro-3-(difluoromethyl)-5-fluoropyridine (CAS 1804950-73-9), a certified reference material (molecular formula C6H3ClF3N, MW 181.54 g/mol) for analytical method development and quality control.

4-Chloro-3-(difluoromethyl)-5-fluoropyridine (C6H3ClF3N) contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-Chloro-3-(difluoromethyl)-5-fluoropyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC6H3ClF3N
Molecular Weight181.54 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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