Palonosetron Impurity 14 CAS 177932-92-2
| CAS No. | 177932-92-2 |
| Molecular Formula | C18H24N2O |
| Molecular Weight | 284.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Palonosetron Impurity 14 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Palonosetron Impurity 14 (CAS 177932-92-2) is a certified pharmaceutical impurity reference standard with the molecular formula C18H24N2O and a molecular weight of 284.40 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Palonosetron Impurity 14 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Palonosetron Impurity 14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H24N2O |
| Molecular Weight | 284.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Nitrogen Atoms | 2 |
Related Palonosetron Standards
- Palonosetron Impurity 13 (CAS 2216753-67-0)
- Palonosetron Impurity 15 (CAS 135729-78-1)
- Palonosetron Impurity 24 (CAS 177793-79-2)
- Palonosetron Impurity 30 (CAS CATO-C4X-110530)
- Palonosetron Impurity N15 (CAS 1796933-62-4)
- Palonosetron Impurity 36 (CAS CATO-C4X-110536)
- Palonosetron Impurity 16 (CAS 177793-80-5)
- Palonosetron Impurity 35 (CAS CATO-C4X-110535)
Recommended Standards
- 351994-94-0 4U7K5X4ANS Emeramide [INN] UNII-4U7K5X4ANS Emeramide 1,3-Benzenedicarboxamide, N1,N3-bis(2-mercaptoethyl)- N,N'-Bis(2-mercaptoethyl)isophthalamide (CAS 351994-94-0)
- tert-butyl 4-[4-(methylamino)pyrazol-1-yl]piperidine-1-carboxylate (CAS 2504240-17-7)
- S-(Phenethylcarbamothioyl)-L-cysteine (CAS 53330-02-2)
- Chlorpheniramine Impurity 14 (CAS CATO-C4X-118814)
- Vonoprazan Impurity 215 (CAS 1993-03-9)
- Landiolol Impurity 53 (CAS 64704-12-7)
- Epinephrine Impurity 77 HCl (CAS 2947-03-7(free base))
- 6-Chloro-4-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline (CAS 1783561-93-2)
- 2-Chloro-4-sec-butyl-phenol (CAS 33129-81-6)
- N,3-dimethylpyridin-2-amine (CAS 156267-13-9)
- 2-(Difluoromethyl)-3-hydroxy-4-(trifluoromethoxy)pyridine-5-acetic acid (CAS 1806160-48-4)
- 1',3',3'-Trimethylspiro[chromene-2,2'-indolin]-6-ol (CAS 23001-29-8)
- 5-bromo-1-(4-fluorophenyl)-1H-pyrazole (CAS 1245149-36-3)
- SAMS Peptide (CAS 125911-68-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com