2,4-Bis(trifluoromethyl)phenylacetic Acid CAS 177952-39-5
| CAS No. | 177952-39-5 |
| Molecular Formula | C10H6F6O2 |
| Molecular Weight | 272.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,4-Bis(trifluoromethyl)phenylacetic Acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,4-Bis(trifluoromethyl)phenylacetic Acid (CAS 177952-39-5) is a high-purity analytical reference standard with the molecular formula C10H6F6O2 and a molecular weight of 272.14 g/mol.
Structurally, 2,4-Bis(trifluoromethyl)phenylacetic Acid (C10H6F6O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 272.14 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2,4-Bis(trifluoromethyl)phenylacetic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6F6O2 |
| Molecular Weight | 272.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
Related Bis Standards
- 3,5-Bis(trifluoromethyl)-2-methoxybenzaldehyde (CAS 197015-73-9)
- 2-[2,5-bis(trifluoromethyl)phenyl]acetic acid (CAS 302912-02-3)
- 3’,5’-Bis(trifluoromethyl)-2-hydroxyacetophenone (CAS 944277-15-0)
- 3,5-Bis(trifluoromethyl)phenylacetic acid (CAS 85068-33-3)
- 3,5-Bis(trifluoromethyl)benzamidoxime (CAS 72111-09-2)
- 3,5-Bis(trifluoromethyl)benzohydrazide (CAS 26107-82-4)
- 2,5-Bis(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7(1H)-one (CAS 198953-52-5)
- 4,6-Bis(trifluoromethyl)-1,2-dihydro-2-thioxopyridine-3-carbonitrile (CAS 265665-03-0)
Recommended Standards
- 3-Bromo-5-((1R,3R)-3-methoxycyclopentyl)pyrazin-2-amine (CAS 1715030-01-5)
- 1-(7-Bromonaphthalen-1-yl)cyclopropane-1-carbonitrile (CAS 1800258-89-2)
- 3-Bromo-5-((2R,4R)-2-methyltetrahydro-2H-pyran-4-yl)pyrazin-2-amine (CAS 1715029-85-8)
- 2-Methoxy-4,6-bis(trifluoromethyl)benzaldehyde (CAS 180134-14-9)
- 4-Chloro-2-methoxy-1-(4-methoxyphenyl)benzene (CAS 1365271-31-3)
- (1R,5S)-6,6-Dimethylbicyclo[3.1.0]hexan-3-one (CAS 13855-29-3)
- 2-(Dimethylamino)-N-(2-(pyrrolidin-2-yl)ethyl)acetamide (CAS 1361113-65-6)
- 5-Fluoro-2-methoxy-4-nitrobenzyl Alcohol (CAS 2006278-11-9)
- 2-Cyclobutylthiazole-4-carboxamide (CAS 1893280-35-7)
- 3-(3-Phenylpropyl)-pyrrolidine (CAS 1220038-62-9)
- 2-Amino-N-ethyl-N-(4-nitrobenzyl)acetamide (CAS 760137-23-3)
- 4-Formyl-2-methoxyphenyl β-D-Glucopyranosiduronic Acid Triacetate Methyl Ester (CAS 704885-44-9)
- Dexrazoxane Impurity 13 (CAS CATO-C4X-202013)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
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